Orofacial clefts are the most common craniofacial birth defects and one of the most common
congenital malformations in humans. They require complex multidisciplinary treatment and …

Orofacial clefts are common birth defects of multifactorial etiology. Several novel approaches
have recently been applied to investigate the causes of clefts. These include examining …

Orofacial clefts are congenital structural anomalies of the lip and/or palate that affect∼
1/1000 live births. Their frequent occurrence as well as their extensive psychological …

With an average worldwide prevalence of approximately 1.2/1000 live births, orofacial clefts
are the most common craniofacial birth defects in humans. Like other complex disorders …

Craniofacial development involves several complex tissue movements including several
fusion processes to form the frontonasal and maxillary structures, including the upper lip and …

Clefts of the lip and/or palate (CL/P) are among the most common birth defects worldwide.
The majority are non-syndromic where CL/P occurs in isolation of other phenotypes. Where …

Orofacial clefts (cleft lip, cleft palate) are among the most common of all major birth defects,
but very little is known about their causation. Genetic factors are thought to play a major role …

Orofacial clefts are common birth defects and can occur as isolated, nonsyndromic events or
as part of Mendelian syndromes. There is substantial phenotypic diversity in individuals with …

Children with oral clefts show a wide range of dental anomalies, adding complexity to
understanding the phenotypic spectrum of orofacial clefting. The evidence is mixed …

Cleft lip with or without cleft palate is the most common facial birth defect and it is caused by
a complex interaction between genetic and environmental factors. The purpose of this …