Metagenomic insight into microbiome and antibiotic resistance genes of high clinical concern in urban and rural hospital wastewater of northern India origin: a major …

A Talat, KS Blake, G Dantas, AU Khan - Microbiology spectrum, 2023 - Am Soc Microbiol
India is one of the largest consumers and producers of antibiotics and a hot spot for the
emergence and proliferation of antimicrobial resistance genes (ARGs). Indian hospital …

[HTML][HTML] Metagenomic survey reveals more diverse and abundant antibiotic resistance genes in municipal wastewater than hospital wastewater

D Zhang, Y Peng, CL Chan, H On, HKF Wai… - Frontiers in …, 2021 - frontiersin.org
Alongside antibiotic resistance, co-selection of antibiotics, biocides, and metal resistance is
a growing concern. While hospital wastewater is considered a hotspot for antibiotic-resistant …

Deciphering basic and key traits of antibiotic resistome in influent and effluent of hospital wastewater treatment systems

L Zhu, L Yuan, XY Shuai, ZJ Lin, YJ Sun, ZC Zhou… - Water Research, 2023 - Elsevier
Hospital wastewater treatment system (HWTS) is an important source and environmental
reservoir of clinically relevant antibiotic resistance genes (ARGs). However, how antibiotic …

[HTML][HTML] Functional repertoire of antibiotic resistance genes in antibiotic manufacturing effluents and receiving freshwater sediments

JJ González-Plaza, A Šimatović, M Milaković… - Frontiers in …, 2018 - frontiersin.org
Environments polluted by direct discharges of effluents from antibiotic manufacturing are
important reservoirs for antibiotic resistance genes (ARGs), which could potentially be …

[HTML][HTML] Sewage effluent from an Indian hospital harbors novel carbapenemases and integron-borne antibiotic resistance genes

NP Marathe, F Berglund, M Razavi, C Pal, J Dröge… - Microbiome, 2019 - Springer
Background Hospital wastewaters contain fecal material from a large number of individuals,
of which many are undergoing antibiotic therapy. It is, thus, plausible that hospital …

New insights into antibiotic resistome in drinking water and management perspectives: a metagenomic based study of small-sized microbes

L Ma, B Li, T Zhang - Water research, 2019 - Elsevier
The proliferation of antibiotic resistance genes (ARGs) in drinking water and their potential
horizontal transfer to pathogenic microbes may cause failure of antibiotics. However …

[HTML][HTML] Secrets of the hospital underbelly: patterns of abundance of antimicrobial resistance genes in hospital wastewater vary by specific antimicrobial and bacterial …

MR Perry, HC Lepper, L McNally, BA Wee… - Frontiers in …, 2021 - frontiersin.org
Background: Hospital wastewater is a major source of antimicrobial resistance (AMR)
outflow into the environment. This study uses metagenomics to study how hospital clinical …

[HTML][HTML] Antibiotic resistance: Global health crisis and metagenomics

S Yadav, A Kapley - Biotechnology Reports, 2021 - Elsevier
Antibiotic resistance is a global problem which affects human health. The imprudent use of
antibiotics (medicine, agriculture, aquaculture, and food industry) has resulted in the broader …

[HTML][HTML] Characterization of metagenomes in urban aquatic compartments reveals high prevalence of clinically relevant antibiotic resistance genes in wastewaters

C Ng, M Tay, B Tan, TH Le, L Haller, H Chen… - Frontiers in …, 2017 - frontiersin.org
The dissemination of antimicrobial resistance (AMR) is an escalating problem and a threat to
public health. Comparative metagenomics was used to investigate the occurrence of …

[HTML][HTML] Population-based variations of a core resistome revealed by urban sewage metagenome surveillance

W Li, F Mao, C Ng, MC Jong, SG Goh, FR Charles… - Environment …, 2022 - Elsevier
Sewage-based surveillance is widely employed to understand the occurrence and
distribution of antimicrobial resistance (AMR) in urban community. However, there are …