Cardiac macrophages are abundant in the healthy heart and after myocardial infarction (MI).
Different macrophage phenotypes likely promote myocardial health vs. disease. Infarct …

Cardiovascular diseases, such as myocardial infarction (MI), are a leading cause of death
worldwide. Acute MI (AMI) inflicts massive injury to the coronary microcirculation, causing …

The heart contains a population of resident macrophages that markedly expands following
injury through recruitment of monocytes and through proliferation of macrophages. In …

Cardiovascular diseases are the leading cause of mortality worldwide. It is widely known
that non-resolving inflammation results in atherosclerotic conditions, which are responsible …

Macrophages play critical roles in homeostatic maintenance of the myocardium under
normal conditions and in tissue repair after injury. In the steady-state heart, resident cardiac …

Ischemic heart disease is a common condition and a leading cause of mortality and
morbidity. Macrophages, besides their role in host defense and tissue homeostasis, are …

Improvements in early interventions after acute myocardial infarction (AMI), notably, the
increased use of timely reperfusion therapy, have increased survival dramatically in recent …

Macrophages are integral components of cardiac tissue and exert profound effects on the
healthy and diseased heart. Paradigm shifting studies using advanced molecular …

Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …

Understanding tissue macrophage biology has become challenging in recent years due the
ever-increasing complexity in macrophage-subset identification and functional …