Protein–lipid interactions and surface activity in the pulmonary surfactant system
AG Serrano, J Pérez-Gil - Chemistry and physics of lipids, 2006 - Elsevier
Pulmonary surfactant is a lipid–protein complex, synthesized and secreted by the respiratory
epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface …
epithelium of lungs to the alveolar spaces, whose main function is to reduce the surface …
Secondary structure and orientation of the surfactant protein SP-B in a lipid environment. A Fourier transform infrared spectroscopy study
G Vandenbussche, A Clercx, M Clercx, T Curstedt… - Biochemistry, 1992 - ACS Publications
Revised Manuscript Received July 10, 1992 abstract: Attenuated total reflection Fourier
transform infrared spectroscopy was used to investigate the secondary structure of the …
transform infrared spectroscopy was used to investigate the secondary structure of the …
[HTML][HTML] Role of pulmonary surfactant components in surface film formation and dynamics
EJA Veldhuizen, HP Haagsman - Biochimica et biophysica acta (bba) …, 2000 - Elsevier
Pulmonary surfactant is a mixture of lipids and proteins which is secreted by the epithelial
type II cells into the alveolar space. Its main function is to reduce the surface tension at the …
type II cells into the alveolar space. Its main function is to reduce the surface tension at the …
Secondary structure and lipid interactions of the N-terminal segment of pulmonary surfactant SP-C in Langmuir films: IR reflection− absorption spectroscopy and …
Pulmonary surfactant, a thin lipid/protein film lining mammalian lungs, functions in vivo to
reduce the work of breathing and to prevent alveolar collapse. Analogues of two …
reduce the work of breathing and to prevent alveolar collapse. Analogues of two …
Dynamic surface properties of pulmonary surfactant proteins SP-B and SP-C and their mixtures with dipalmitoylphosphatidylcholine
SG Taneva, KMW Keough - Biochemistry, 1994 - ACS Publications
Revised Manuscript Received September 2, 1994s abstract: Dynamic cyclic surface
pressure (jr)-area measurements were performed on surfactant proteins SP-B and SP-C in …
pressure (jr)-area measurements were performed on surfactant proteins SP-B and SP-C in …
Interaction of lung surfactant proteins with anionic phospholipids
DY Takamoto, MM Lipp, A Von Nahmen, KYC Lee… - Biophysical journal, 2001 - cell.com
Langmuir isotherms, fluorescence microscopy, and atomic force microscopy were used to
study lung surfactant specific proteins SP-B and SP-C in monolayers of …
study lung surfactant specific proteins SP-B and SP-C in monolayers of …
[HTML][HTML] Pulmonary surfactant: functions and molecular composition
J Goerke - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 1998 - Elsevier
This review briefly notes recent findings important for understanding the surface mechanical
functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are …
functions of pulmonary surfactant. Currently known surfactant-specific proteins and lipids are …
[HTML][HTML] Structure of pulmonary surfactant membranes and films: the role of proteins and lipid–protein interactions
J Pérez-Gil - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2008 - Elsevier
The pulmonary surfactant system constitutes an excellent example of how dynamic
membrane polymorphism governs some biological functions through specific lipid–lipid …
membrane polymorphism governs some biological functions through specific lipid–lipid …
Structure-function relationships of bovine pulmonary surfactant proteins: SP-B and SP-C
A Takahashi, AJ Waring, J Amirkhanian, B Fan… - … et Biophysica Acta (BBA …, 1990 - Elsevier
Pulmonary surfactant contains at least three unique proteins: SP-A, SP-B and SP-C. SP-B
and SP-C from bovine surfactant are markedly hydrophobic and have molecular masses …
and SP-C from bovine surfactant are markedly hydrophobic and have molecular masses …
Combined and independent action of proteins SP-B and SP-C in the surface behavior and mechanical stability of pulmonary surfactant films
The hydrophobic proteins SP-B and SP-C are essential for pulmonary surfactant function,
even though they are a relatively minor component (< 2% of surfactant dry mass). Despite …
even though they are a relatively minor component (< 2% of surfactant dry mass). Despite …
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