Dental pain is a common health problem that negatively impacts the activities of daily living.
Dentine hypersensitivity and pulpitis-associated pain are among the most common types of …

The mechanism of pain in dentine hypersensitivity is poorly understood but proposed to
result from the activation of dental sensory neurons in response to dentinal fluid movements …

Odontoblasts form the outermost cellular layer of the dental pulp where they have been
proposed to act as sensory receptor cells. Despite this suggestion, evidence supporting their …

Hypersensitivity to thermal and mechanical stimuli can occur in painful pulpitis. To explore
the neuro-anatomical basis of heat and mechanical sensitivity, we evaluated expression of …

The tooth has an unusual sensory system that converts external stimuli predominantly into
pain, yet its sensory afferents in teeth demonstrate cytochemical properties of non …

OBJECTIVE: Transient receptor potential (TRP) channels, a family of structurally related
proteins have been implicated in the sensation of pain and hyperalgesia caused by …

Transient receptor potential (TRP) ion channels are critical contributors to the perception of
various environmental stimuli. Although the oral cavity is the access point for various food …

Odontoblasts have been suggested to contribute to nociceptive sensation in the tooth via
expression of the transient receptor potential (TRP) channels. The TRP channels as a family …

Orofacial pain, including temporomandibular joint disorders pain, trigeminal neuralgia,
dental pain, and debilitating headaches, affects millions of Americans each year with …

Introduction The transient receptor potential (TRP) ion channels have emerged as important
cellular sensors in both neuronal and non-neuronal cells, with TRPA1 playing a central role …