Beneficial effects of ischemic preconditioning on pancreas cold preservation
AR Hogan, M Doni, RD Molano… - Cell …, 2012 - journals.sagepub.com
Ischemic preconditioning (IPC) confers tissue resistance to subsequent ischemia in several
organs. The protective effects are obtained by applying short periods of warm ischemia …
organs. The protective effects are obtained by applying short periods of warm ischemia …
Ischemic preconditioning improves islet recovery after pancreas cold preservation
AR Hogan, M Doni, MM Ribeiro, RD Molano… - Transplantation …, 2009 - Elsevier
Increasing evidence supports the beneficial effects of ischemic preconditioning (IPC) of
organs on subsequent ischemia. The aim of this study was to assess the effects of IPC of the …
organs on subsequent ischemia. The aim of this study was to assess the effects of IPC of the …
Ischemic preconditioning fails to improve microcirculation but increases apoptotic cell death in experimental pancreas transplantation
O Drognitz, X Liu, R Obermaier, H Neeff… - Transplant …, 2004 - Wiley Online Library
Brief periods of warm ischemia and subsequent short reperfusion before either long‐term
cold or warm ischemic insult (ischemic preconditioning, IPC) have proven to ameliorate …
cold or warm ischemic insult (ischemic preconditioning, IPC) have proven to ameliorate …
Effects of pancreas cold ischemia on islet function and quality
We used a rat model of pancreas cold preservation to assess its effects on islets. Glands
were surgically retrieved and stored in University of Wisconsin (UW) solution for 3 hours …
were surgically retrieved and stored in University of Wisconsin (UW) solution for 3 hours …
Impact of pancreatic cold preservation on rat islet recovery and function
Background. Islet transplantation success depends on the number and quality of islets
transplanted. This study aimed at exploring the molecular mechanisms associated with cold …
transplanted. This study aimed at exploring the molecular mechanisms associated with cold …
Mechanisms of islet damage mediated by pancreas cold ischemia/rewarming
K Omori, E Kobayashi, J Rawson, M Takahashi… - Cryobiology, 2016 - Elsevier
Prolonged pancreas cold ischemia is known to negatively correlate with islet isolation
outcomes, hindering successful islet transplantation to treat Type-1 Diabetes. Due to poor …
outcomes, hindering successful islet transplantation to treat Type-1 Diabetes. Due to poor …
Ischemic preconditioning and liver tolerance to warm or cold ischemia: experimental studies in large animals
P Compagnon, S Lindell, MS Ametani, B Gilligan… - …, 2005 - journals.lww.com
Background. In the rodent, ischemic preconditioning (IPC) has been shown to improve the
tolerance of the liver to ischemia-reperfusion under normothermic or hypothermic conditions …
tolerance of the liver to ischemia-reperfusion under normothermic or hypothermic conditions …
Heat shock preconditioning impairs revascularization of freely transplanted pancreatic islets1
R Schramm, C Scheuer, J Yamauchi, B Vollmar… - …, 2002 - journals.lww.com
Background. Revascularization of freely transplanted pancreatic islets is essential for
appropriate graft function and survival. During the first days after transplantation, however …
appropriate graft function and survival. During the first days after transplantation, however …
Ischemic preconditioning in a rodent hepatocyte model of liver hypothermic preservation injury
P Compagnon, HB Wang, JH Southard, MJ Mangino - Cryobiology, 2002 - Elsevier
Ischemic preconditioning (IPC) is a phenomenon of protection in various tissues from
normothermic ischemic injury by previous exposure to short cycles of ischemia–reperfusion …
normothermic ischemic injury by previous exposure to short cycles of ischemia–reperfusion …
Hypothermic perfusion preservation of pancreas for islet grafts: validation using a split lobe porcine model
BP Weegman, MJ Taylor, SC Baicu, WE Scott… - 2011 - journals.sagepub.com
The demand for high-quality islets for transplantation in type I diabetics will increase as the
current clinical trials transition into standard of care. The mode of preservation of donor …
current clinical trials transition into standard of care. The mode of preservation of donor …
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