The autonomic nervous system regulates gastric ghrelin secretion in rats

H Hosoda, K Kangawa - Regulatory peptides, 2008 - Elsevier
Plasma ghrelin levels are responsive to short-and long-term nutrient fluctuation, but the
mechanisms of its regulation are largely unknown. To explore the role of the autonomic …

[PDF][PDF] Role for central ghrelin in food intake and secretion profile of stomach ghrelin in rats

N Murakami, T Hayashida, T Kuroiwa… - Journal of …, 2002 - Citeseer
Abstract Ghrelin, a 28-amino-acid peptide, has recently been isolated from the rat stomach
as an endogenous ligand for the GH secretagogue receptor. We have reported previously …

Changes in ghrelin and ghrelin receptor expression according to feeding status

MS Kim, CY Yoon, KH Park, CS Shin, KS Park… - …, 2003 - journals.lww.com
Ghrelin, a newly identified gut hormone, has been implicated in the regulation of food intake
and energy homeostasis. This study was undertaken to investigate changes in expression …

Post-prandial decrease of circulating human ghrelin levels

M Tschöp, R Wawarta, RL Riepl, S Friedrich… - Journal of …, 2001 - Springer
Ghrelin, an endogenous ligand of the GH secretagogue-receptor, has recently been shown
to stimulate GH secretion and to have orexigenic and adipogenic effects in rodents, but little …

Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration

K Toshinai, MS Mondal, M Nakazato, Y Date… - Biochemical and …, 2001 - Elsevier
Ghrelin is a novel gut–brain peptide that binds to the growth hormone secretagogue
receptor (GHS-R), thereby functioning in the regulation of growth hormone (GH) release and …

Ghrelin acts on the dorsal vagal complex to stimulate pancreatic protein secretion

Y Li, X Wu, Y Zhao, S Chen… - American Journal of …, 2006 - journals.physiology.org
Ghrelin receptors are present in the central nervous system. We hypothesized that ghrelin
released from the stomach acts as an endocrine substance and stimulates brain stem …

Vagotomy dissociates short-and long-term controls of circulating ghrelin

DL Williams, HJ Grill, DE Cummings… - Endocrinology, 2003 - academic.oup.com
Plasma ghrelin levels are responsive to short-and long-term nutrient fluctuation, rapidly
decreasing with food consumption and increasing with food deprivation or weight loss. We …

The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

Y Date, N Murakami, K Toshinai, S Matsukura… - Gastroenterology, 2002 - Elsevier
Background & Aims: Visceral sensory information is transmitted to the brain through the
afferent vagus nerve. Ghrelin, a peptide primarily produced in the stomach, stimulates both …

Enhanced plasma ghrelin levels in rats with streptozotocin‐induced diabetes

T Masaoka, H Suzuki, H Hosoda, T Ota… - FEBS …, 2003 - Wiley Online Library
Ghrelin is a novel gastrointestinal peptide that stimulates growth hormone secretion, food
intake, and body weight gain. Increased ghrelin secretion has been reported in such …

Effects of insulin, leptin, and glucagon on ghrelin secretion from isolated perfused rat stomach

J Kamegai, H Tamura, T Shimizu, S Ishii, H Sugihara… - Regulatory peptides, 2004 - Elsevier
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, was
originally purified from the rat stomach. Although ghrelin has been recognized as an …