Gut microbiota profile identifies transition from compensated cardiac hypertrophy to heart failure in hypertensive rats

E Gutiérrez-Calabrés, A Ortega-Hernández… - …, 2020 - Am Heart Assoc
Microcirculatory alterations displayed by patients with heart failure (HF) induce structural
and functional intestinal changes that may affect normal gut microbial community. At the …

[HTML][HTML] Heart failure severity closely correlates with intestinal dysbiosis and subsequent metabolomic alterations

ME Spehlmann, AY Rangrez, DP Dhotre, N Schmiedel… - Biomedicines, 2022 - mdpi.com
Growing evidence suggests an altered gut microbiome in patients with heart failure (HF).
However, the exact interrelationship between microbiota, HF, and its consequences on the …

[HTML][HTML] Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure

T Kamo, H Akazawa, W Suda, A Saga-Kamo… - PloS one, 2017 - journals.plos.org
Emerging evidence has suggested a potential impact of gut microbiota on the
pathophysiology of heart failure (HF). However, it is still unknown whether HF is associated …

Quantifying the impact of gut microbiota on inflammation and hypertensive organ damage

EG Avery, H Bartolomaeus, A Rauch… - Cardiovascular …, 2023 - academic.oup.com
Aims Hypertension (HTN) can lead to heart and kidney damage. The gut microbiota has
been linked to HTN, although it is difficult to estimate its significance due to the variety of …

[HTML][HTML] Changes of gut microbiome composition and metabolites associated with hypertensive heart failure rats

L Li, S Zhong, S Hu, B Cheng, H Qiu, Z Hu - BMC microbiology, 2021 - Springer
Background The potential role of the gut microbiome (GM) in heart failure (HF) had recently
been revealed. However, the underlying mechanisms of the GM and fecal metabolome in …

[HTML][HTML] Gut microbiota dysbiosis contributes to the development of hypertension

J Li, F Zhao, Y Wang, J Chen, J Tao, G Tian, S Wu… - Microbiome, 2017 - Springer
Background Recently, the potential role of gut microbiome in metabolic diseases has been
revealed, especially in cardiovascular diseases. Hypertension is one of the most prevalent …

Microbiota introduced to germ-free rats restores vascular contractility and blood pressure

B Joe, CG McCarthy, JM Edwards, X Cheng… - …, 2020 - Am Heart Assoc
Commensal gut microbiota are strongly correlated with host hemodynamic homeostasis but
only broadly associated with cardiovascular health. This includes a general correspondence …

Alterations in the gut microbiota can elicit hypertension in rats

S Adnan, JW Nelson, NJ Ajami… - Physiological …, 2017 - journals.physiology.org
Gut dysbiosis has been linked to cardiovascular diseases including hypertension. We tested
the hypothesis that hypertension could be induced in a normotensive strain of rats or …

[HTML][HTML] The implication of the gut microbiome in heart failure

VV Lupu, A Adam Raileanu, CM Mihai, ID Morariu… - Cells, 2023 - mdpi.com
Heart failure is a worldwide health problem with important consequences for the overall
wellbeing of affected individuals as well as for the healthcare system. Over recent decades …

[HTML][HTML] Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients

X Cui, L Ye, J Li, L Jin, W Wang, S Li, M Bao, S Wu… - Scientific reports, 2018 - nature.com
Previous studies suggested a possible gut microbiota dysbiosis in chronic heart failure
(CHF). However, direct evidence was lacking. In this study, we investigated the composition …