Effect of fecal microbiota transplantation on primary hypertension and the underlying mechanism of gut microbiome restoration: protocol of a randomized, blinded …

L Fan, J Ren, Y Chen, Y Wang, Z Guo, P Bu, J Yang… - Trials, 2022 - Springer
Background Hypertension is currently the leading modifiable cause of global morbidity and
mortality, leading to substantial health and financial burdens. Although multiple studies of …

The gut microbiota and its interactions with cardiovascular disease

H Xu, X Wang, W Feng, Q Liu, S Zhou… - Microbial …, 2020 - Wiley Online Library
The intestine is colonized by a considerable community of microorganisms that cohabits
within the host and plays a critical role in maintaining host homeostasis. Recently …

The effect of diet on hypertensive pathology: is there a link via gut microbiota-driven immunometabolism?

HA Jama, A Beale, WA Shihata… - Cardiovascular …, 2019 - academic.oup.com
Over the past decade, the immune system has emerged as an important component in the
aetiology of hypertension. There has been a blooming interest in the contribution of the gut …

Altered Gut Microbiota is Involved in the Anti‐Hypertensive Effects of Vitamin C in Spontaneously Hypertensive Rat

Y Li, RM Salih Ibrahim, HL Chi, T Xiao… - Molecular Nutrition & …, 2021 - Wiley Online Library
Scope Gut dysbiosis and dysregulation of the gut‐brain‐axis contributes to the pathogenesis
of hypertension. Vitamin C (VC) is a common dietary supplement that shows the ability to …

Targeting gut microbiota as a novel strategy for prevention and treatment of hypertension, atrial fibrillation and heart failure: current knowledge and future perspectives

OM Drapkina, AA Yafarova, AN Kaburova, AR Kiselev - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) remain the major public health concern worldwide. Over
the last two decades, a considerable amount of literature has been published on gut …

Gut microbiota and derived short-chain fatty acids are linked to evolution of heart failure patients

J Modrego, A Ortega-Hernández… - International journal of …, 2023 - mdpi.com
There is a lack of direct evidence regarding gut microbiota dysbiosis and changes in short-
chain fatty acids (SCFAs) in heart failure (HF) patients. We sought to assess any association …

Non-ischemic heart failure with reduced ejection fraction is associated with altered intestinal microbiota

T Katsimichas, T Ohtani, D Motooka… - Circulation …, 2018 - jstage.jst.go.jp
Background: Research suggests that heart failure with reduced ejection fraction (HFrEF) is a
state of systemic inflammation that may be triggered by microbial products passing into the …

Recent advances in modulation of cardiovascular diseases by the gut microbiota

SK Masenga, B Hamooya, J Hangoma… - Journal of Human …, 2022 - nature.com
The gut microbiota has recently gained attention due to its association with cardiovascular
health, cancers, gastrointestinal disorders, and non-communicable diseases. One critical …

[HTML][HTML] Commensal gut microbiota-derived acetate and propionate enhance heart adaptation in response to cardiac pressure overload in mice

CJ Lin, YC Cheng, HC Chen, YK Chao… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: The gut microbiota plays a vital role in maintaining tissue homeostasis and
regulating disease pathophysiology; however, the underlying mechanisms remain to be …

The gut microbiome of heart failure with preserved ejection fraction

AL Beale, JA O'Donnell, ME Nakai… - Journal of the …, 2021 - Am Heart Assoc
Background Risk factors for heart failure with preserved ejection fraction (HFpEF) include
hypertension, age, sex, and obesity. Emerging evidence suggests that the gut microbiota …