Interferon gamma-1b therapy for advanced idiopathic pulmonary fibrosis

S Kalra, JP Utz, JH Ryu… - Mayo Clinic …, 2003 - Elsevier
OBJECTIVE To report on observations made in a group of patients with idiopathic
pulmonary fibrosis/usual interstitial pneumonia (IPF/UIP) who were treated with interferon …

Long-term survival in idiopathic pulmonary fibrosis patients treated with interferon gamma-1b.(Interstitial lung disease: outcomes: 2: 00pm-3: 30pm)

R Ziesche, WZ Bradford, M Crager, LH Block - Chest, 2002 - go.gale.com
PURPOSE: Idiopathic Pulmonary Fibrosis (IPF) is characterized by progressive respiratory
insufficiency and a median survival of only 2-5 years. There is no therapy for IPF with …

A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis

G Raghu, KK Brown, WZ Bradford… - … England Journal of …, 2004 - Mass Medical Soc
Background Idiopathic pulmonary fibrosis is a progressive, fatal disease with no known
efficacious therapy. Methods In a double-blind, multinational trial, we randomly assigned …

Interferon gamma-1b in the treatment of idiopathic pulmonary fibrosis

MA Pacanowski, GW Amsden - Annals of Pharmacotherapy, 2005 - journals.sagepub.com
Objective: To examine the clinical aspects of idiopathic pulmonary fibrosis (IPF) and the
efficacy and safety of interferon gamma-1b (IFNγ− 1b) in its treatment. Data Sources …

Interferon gamma-1b as therapy for idiopathic pulmonary fibrosis: an intrapatient analysis

SD Nathan, SD Barnett, B Moran, DL Helman… - Respiration, 2004 - karger.com
Background: The only proven therapeutic option for idiopathic pulmonary fibrosis (IPF) is
lung transplantation. It is biologically plausible that interferon gamma-1b (G-IFN) may halt or …

Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial

TE King, C Albera, WZ Bradford, U Costabel, P Hormel… - The Lancet, 2009 - thelancet.com
Background Idiopathic pulmonary fibrosis is a fatal disease for which no effective treatment
exists. We assessed whether treatment with interferon gamma-1b improved survival …

Interferon-γ1b therapy in idiopathic pulmonary fibrosis: a metaanalysis

EK Bajwa, NT Ayas, M Schulzer, E Mak, JH Ryu… - Chest, 2005 - Elsevier
Context Despite the investigation of multiple therapeutic options, idiopathic pulmonary
fibrosis (IPF) remains a devastating, progressively fatal disease. Much interest has focused …

Long-term clinical effects of interferon gamma-1b and colchicine in idiopathic pulmonary fibrosis

KM Antoniou, AG Nicholson, M Dimadi… - European …, 2006 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF)/usual interstitial pneumonia is a deadly disease with no
effective treatment. The purpose of this randomised prospective multicentric study was to …

Does interferon‐γ improve pulmonary function in idiopathic pulmonary fibrosis?

A Prasse, KM Müller, C Kurz, H Hamm… - European Respiratory …, 2003 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a disease with progressive and devastating
deterioration of lung function and a fatal prognosis, despite aggressive therapeutic attempts …

The clinical course of patients with idiopathic pulmonary fibrosis

FJ Martinez, S Safrin, D Weycker, KM Starko… - Annals of internal …, 2005 - acpjournals.org
Background: Prospective data defining the clinical course in idiopathic pulmonary fibrosis
(IPF) are sparse. Objective: To analyze the clinical course of patients with mild to moderate …