Epidemiological studies have shown that lower birthweight is associated with a wide range
of adverse outcomes in later life, including poorer 'human capital'(shorter stature, lower …

Renewed interest in nutrition during pregnancy has been generated by the hypothesis that
adult disease has origins in early life. Animal experiments clearly show that altering …

Similarities in offspring phenotype due to maternal under-or over-nutrition during gestation
have been observed in studies conducted at University of Wyoming. In these studies, ewes …

Recent findings suggest that many human fetuses have to adapt to a limited supply of
nutrients and in doing so they permanently change their physiology and metabolism. These …

SUMMARY 1 INTRODUCTION 2 PHYSIOLOGICAL CHANGES DURING PREGNANCY 2.1
Changes in body composition and weight gain 2.2 Changes in blood composition 2.3 …

The “developmental origins of health and disease”(DOHaD) hypothesis proposes that
environmental conditions during fetal and early post-natal development influence lifelong …

The relationship between maternal nutrition and fetal growth is more complex than might be
at first assumed. Low birthweight (LBW) increases the risk of early mortality and later …

Individuals who were small at birth have an increased risk of cardiovascular disease in later
life. Barker has put forward a hypothesis to explain this and other associations, known as the …

Over the last decade epidemiological studies have suggested that the risk of coronary heart
disease, stroke mortality and hypertension is, in part, related to the environment …

The simple relationship between maternal macro-nutrient status and perinatal survival
(increased ma-cronutrient intake→ increased maternal weight and/or weight gain→ …