Insight into the pediatric and adult dichotomy of COVID‐19: age‐related differences in the immune response to SARS‐CoV‐2 infection

A Fialkowski, Y Gernez, P Arya… - Pediatric …, 2020 - Wiley Online Library
The difference in morbidity and mortality between adult and pediatric coronavirus disease
2019 infections is dramatic. Understanding pediatric‐specific acute and delayed immune …

[HTML][HTML] Immunology of SARS-CoV-2 infection in children

J Chou, PG Thomas, AG Randolph - Nature immunology, 2022 - nature.com
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …

[HTML][HTML] Understanding COVID-19 in children: immune determinants and post-infection conditions

GA Rotulo, P Palma - Pediatric research, 2023 - nature.com
Coronavirus disease 2019 in children presents with milder clinical manifestations than in
adults. On the other hand, the presence of a wide range of inflammatory manifestations …

Immune response to SARS-CoV-2 in children: A review of the current knowledge

F Filippatos, EB Tatsi, A Michos - Pediatric Investigation, 2021 - mednexus.org
Host immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
especially in children, are still under investigation. Children with coronavirus disease 2019 …

[HTML][HTML] Cellular, Antibody and Cytokine Pathways in Children with Acute SARS-CoV-2 Infection and MIS-C—Can We Match the Puzzle?

S Lazova, Y Dimitrova, D Hristova, I Tzotcheva… - Antibodies, 2022 - mdpi.com
The newly identified strain of the Coronaviridae family called severe acute respiratory
syndrome (SARS-CoV-2) recently became the most significant health threat for adults and …

[HTML][HTML] Understanding COVID-19: are children the key?

S Warner, A Richter, Z Stamataki, D Kelly - BMJ Paediatrics Open, 2021 - ncbi.nlm.nih.gov
The devastating impact of the COVID-19 pandemic on global health and economic stability
is immeasurable. The situation is dynamic and fast-evolving, with the world facing new …

[HTML][HTML] Pediatric COVID-19: immunopathogenesis, transmission and prevention

G Blanchard-Rohner, A Didierlaurent, A Tilmanne… - Vaccines, 2021 - mdpi.com
Children are unique in the context of the COVID-19 pandemic. Overall, SARS-CoV-2 has a
lower medical impact in children as compared to adults. A higher proportion of children than …

Age-related differences in immunological responses to SARS-CoV-2

LSY Wong, EXL Loo, AYH Kang, HX Lau… - The Journal of Allergy …, 2020 - Elsevier
There is a striking age-related disparity in the prevalence and severity of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced coronavirus disease 2019 …

[HTML][HTML] Children and SARS-CoV-2

D Bogunovic, M Merad - Cell Host & Microbe, 2021 - cell.com
A previously immune-naive world population is experiencing natural infection with SARS-
CoV-2. Severe COVID-19 predominantly impacts adults, yet multisystem inflammatory …

Age‐related differences in the immune response could contribute to determine the spectrum of severity of COVID‐19

G Costagliola, E Spada… - … inflammation and disease, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), can present with a wide spectrum of
severity. Elderly patients with cardiac, pulmonary and metabolic comorbidities are more …