Upregulated expression of ILF2 in non-small cell lung cancer is associated with tumor cell proliferation and poor prognosis

T Ni, G Mao, Q Xue, Y Liu, B Chen, X Cui, L Lv… - Journal of molecular …, 2015 - Springer
Abstract ILF2 (NF45) is a sequence-specific DNA binding protein that is involved in mitosis
control, transcriptional regulation, DNA breaks repair, microRNA processing and viral …

[HTML][HTML] Interferon regulatory factor 4 (IRF4) is overexpressed in human non‑small cell lung cancer (NSCLC) and activates the Notch signaling pathway

Y Qian, Z Du, Y Xing, T Zhou… - Molecular medicine …, 2017 - spandidos-publications.com
The transcription factor, interferon regulatory factor 4 (IRF4), serves an essential role in the
regulation of immune responses, and has been reported to act as a diagnostic and …

Expression and clinical role of NF45 as a novel cell cycle protein in esophageal squamous cell carcinoma (ESCC)

S Ni, J Zhu, J Zhang, S Zhang, M Li, R Ni, J Liu, H Qiu… - Tumor Biology, 2015 - Springer
NF45 (also known as ILF2), as one subunit of NF-AT (nuclear factor of activated T cells),
repairs DNA breaks, inhibits viral replication, and also functions as a negative regulator in …

[HTML][HTML] Interferon regulatory factor 4 correlated with immune cells infiltration could predict prognosis for patients with lung adenocarcinoma

X Li, S Zhai, J Zhang, D Zhang, S Wang, L Wang… - Frontiers in …, 2021 - frontiersin.org
Background Immune related interferon regulatory factor 4 (IRF4) is a member of the IRF
family, whereas the clinical significance and possible role of IRF4 in lung adenocarcinoma …

Decreased IFIT2 expression in human non-small-cell lung cancer tissues is associated with cancer progression and poor survival of the patients

W Su, W Xiao, L Chen, Q Zhou, X Zheng… - OncoTargets and …, 2019 - Taylor & Francis
Background IFIT2 (interferon-induced proteins with tetratricopeptide repeats 2), also known
as ISG54, is an important interferon-stimulated gene family protein, which has been …

A promising role of interferon regulatory factor 5 as an early warning biomarker for the development of human non-small cell lung cancer

J Guo, X Wang, Y Wang, L Wang, S Hua - Lung Cancer, 2019 - Elsevier
Objectives Non-small cell lung cancer (NSCLC) accounts for 85%–90% of lung cancer
cases and is a covert disease lacking early symptoms. Since cancer is recognised as an …

[HTML][HTML] Immunoglobulin-like transcript 4 promotes tumor progression and metastasis and up-regulates VEGF-C expression via ERK signaling pathway in non-small …

P Zhang, X Guo, J Li, S Yu, L Wang, G Jiang, D Yang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Abstract Immunoglobulin-like transcript (ILT) 4 has long been thought to be cell-surface
molecule in certain immune cells and negatively regulates immune response. Recently …

[HTML][HTML] Interferon consensus sequence-binding protein 8, a tumor suppressor, suppresses tumor growth and invasion of non-small cell lung cancer by interacting with …

L Ye, T Xiang, J Zhu, D Li, Q Shao, W Peng… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Interferon consensus sequence-binding protein 8 (IRF8) belongs to a
family of interferon (IFN) regulatory factors that modulates various important physiological …

[HTML][HTML] COL8A1 promotes NSCLC progression through IFIT1/IFIT3-mediated EGFR activation

X Zan, S Li, S Wei, L Gao, L Zhao, X Yan, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Activation of EGFR is a major risk factor for non-small cell lung cancer (NSCLC).
Understanding the molecular events promoting EGFR activation can help us gain more …

[HTML][HTML] AIF-1, a potential biomarker of aggressive tumor behavior in patients with non-small cell lung cancer

L Wang, X Zhao, H Zheng, C Zhu, Y Liu - PLoS One, 2022 - journals.plos.org
Allogeneic inflammatory factor-1 (AIF-1) overexpression has been reported to be associated
with tumorigenesis and tumor metastasis. This study aimed to investigate the role of AIF-1 in …