EGFR-mediated interleukin enhancer-binding factor 3 contributes to formation and survival of cancer stem-like tumorspheres as a therapeutic target against EGFR …

CC Cheng, KF Chou, CW Wu, NW Su, CL Peng, YW Su… - Lung Cancer, 2018 - Elsevier
Objectives YM155, an inhibitor of interleukin enhancer-binding factor 3 (ILF3), significantly
suppresses cancer stemness property, implying that ILF3 contributes to cell survival of …

KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α

X Li, X Liu, Y Xu, J Liu, M Xie… - … journal of oncology, 2014 - spandidos-publications.com
Transcription factor Krüppel-like factors 5 (KLF5) is overexpressed in a wide range of tumor
tissues and acts as a prognostic factor in cancer. However, the role of KLF5 in non-small cell …

ILF3 promotes gastric cancer proliferation and may be used as a prognostic marker

Y Liu, Y Li, Y Zhao, Y Liu, L Fan… - Molecular Medicine …, 2019 - spandidos-publications.com
Interleukin enhancer‑binding factor 3 (ILF3) may function as a transcriptional coactivator and
has been reported to be involved in tumor proliferation and metastasis; however, its role and …

PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration

J Zhang, Q Ma, Q Yu, F Xiao, Z Zhang, H Feng, C Liang - Biology Direct, 2023 - Springer
Background Proteasome 26S subunit, non-ATPase 3 (PSMD3) has been reported to
participate in various human cancers. Nevertheless, the function of PSMD3 in lung cancer …

Interferon‐induced transmembrane protein 1‐mediated EGFR/SOX2 signaling axis is essential for progression of non‐small cell lung cancer

YG Yang, YW Koh, IN Sari, N Jun, S Lee… - … journal of cancer, 2019 - Wiley Online Library
Emerging data indicate that interferon‐induced transmembrane protein 1 (IFITM1) plays an
important role in many cancers. However, it remains unclear whether IFITM1 is functionally …

Interferon regulatory factor-1 regulates cisplatin-induced apoptosis and autophagy in A549 lung cancer cells

L Zhang, T Cheng, H Yang, J Chen, X Wen, Z Jiang… - Medical Oncology, 2022 - Springer
This study aimed to investigate the expression and function of interferon regulatory factor-1
(IRF-1) in non-small cell lung cancer (NSCLC). IRF-1 expression and its prognostic value …

[HTML][HTML] Downregulation of T-cell cytotoxic marker IL18R1 promotes cancer proliferation and migration and is associated with dismal prognosis and immunity in lung …

Q Guo, CY Wu, N Jiang, S Tong, JH Wan… - Frontiers in …, 2022 - frontiersin.org
Immunotherapy can improve the survival of patients with advanced lung squamous cell
carcinoma (LUSC). T cytotoxic cells are one of the main members of the immune …

Prognostic value of IL‑6R mRNA in lung adenocarcinoma and squamous cell carcinoma

B Xu, Q Chen, C Yue, L Lan, J Jiang… - Oncology …, 2018 - spandidos-publications.com
Previous studies have demonstrated that the interleukin (IL)‑6/IL‑6 receptor (IL‑6R) signaling
pathway contributes to the pathogenesis of lung cancer. Lung adenocarcinoma (LUAD) and …

IFI44L as a novel epigenetic silencing tumor suppressor promotes apoptosis through JAK/STAT1 pathway during lung carcinogenesis

Y Zeng, H Chen, Z Zhang, J Fan, J Li, S Zhou… - Environmental …, 2023 - Elsevier
Numerous evidence showed that the occurrence and development of lung cancer is closely
related to environmental pollution. Therefore, new environmental response predictive …

EIF3C promotes Lung Cancer Tumorigenesis by regulating the APP/HSPA1A/LMNB1 Axis

X Ding, L Hou, H Zhang, Z Chen, Z Liu, J Gong… - Disease …, 2022 - Wiley Online Library
Objective. This study was designed to explore the role and mechanism of eukaryotic
initiation factor 3C (EIF3C) in the proliferation and apoptosis of lung cancer cells. Methods …