Radiation is one of the main methods for the treatment of colorectal cancer (CRC) before or
after surgery. However, radiotherapy tolerance of patients with CRC is often a major …

Abstract ATPase inhibitory factor 1 (IF1), an inhibitor of the mitochondrial H+-adenosine
triphosphate (ATP) synthase, is putatively involved in tumor progression. This study aimed to …

Rab-interacting lysosomal protein–like 2 (RILPL2) has been reported to be associated with
prognosis and tumor biological functions in breast cancer and endometrial carcinoma …

Simple Summary Lung cancer is the leading cause of cancer-related deaths worldwide,
accounting for more than 1.6 million deaths per year. The tumor microenvironment (TME) …

Non-small cell lung cancer (NSCLC) is an aggressive type of lung malignancy. Most of the
patients have poor prognosis. Increasing evidence has revealed an association between …

Background Gene targeted therapy refers to any therapy focused on one of the many
biological features of the tumor. Such features are mediated by specific genes that are …

We have previously isolated an oncogene EIF5A2 (eukaryotic initiation factor 5A2) from a
frequently amplified region at 3q of a primary ovarian cancer cell line, and demonstrated its …

According to previous reports demonstrating the implication of insulin-like growth factor
receptor (IGF-1R) signaling in non-small cell lung cancer (NSCLC), in this study, the …

Small cell lung cancer (SCLC) is a severe malignancy associated with early and widespread
metastasis. To study SCLC metastasis, we previously developed an orthotopic …

Background Interferon alpha-inducible protein 27 (IFI27) is an interferon alpha-inducible
protein, which was found to be upregulated in some cancers, such as breast cancer …