Objective To explore HIF1α and HIF2α regulate the dedifferentiation of lung cancer cells
under hypoxic conditions through Sox2 and Oct4. Materials and methods: HIF1α, HIF2α …

Pancreatic cancer is one of the most malignant diseases in the world. Interferon regulator
factor 2 (IRF-2), an interferon regulatory factor, has been known to act as an oncogene in …

Background The mechanisms involved in the malignant progression of lung
adenocarcinoma (LUAD) are still inconclusive. Fibrinogen-like protein 1 (FGL1) and LAG3 …

Abstract Interleukin 7 (IL‐7) is known to promote lymphangiogenesis. To study the
relationship between IL‐7 and the lymphangiogenesis in lung cancer cells xenograft tumors …

The expression pattern, biological functions and the related mechanisms of the ring finger
protein 19A (RNF19A) in non‐small cell lung cancer (NSCLC) remain poorly understood …

IRF8 is a transcription factor with a critical role in B lymphocyte development and functions.
Its role in human diffuse large B-cell lymphoma (DLBCL), however, remained elusive. In this …

Objective Mitochondria play multifunctional roles in carcinogenesis. Deciphering
uncertainties of molecular interactions within mitochondria will promote further …

IFIT1 and IFIT3 are abundant products of interferon-stimulating genes. While the importance
of IFIT1 and IFIT3 in the prognosis of cancer has been reported, the molecular basis of IFIT1 …

Interferon-induced protein 44 (IFI44) containing a guanosine-5′-triphosphate (GTP)
binding domain was reported to play a significant role in the immune response to …

Krüppel-like factor 8 (KLF8) plays a key role in cancer progression. However, its expression
pattern and relationship with clinicopathological characteristics in non-small cell lung cancer …