Amiodarone: an overview of its pharmacological properties, and review of its therapeutic use in cardiac arrhythmias

J Gill, RC Heel, A Fitton - Drugs, 1992 - Springer
Synopsis Amiodarone, originally developed over 20 years ago, is a potent antiarrhythmic
drug with the actions of all antiarrhythmic drug classes. It has been successfully used in the …

Long-term management of sustained, recurrent, symptomatic ventricular tachycardia with amiodarone.

JC Kaski, LA Girotti, H Messuti, B Rutitzky… - Circulation, 1981 - Am Heart Assoc
Twenty-three patients with sustained, recurrent, symptomatic ventricular tachycardia were
treated with oral amiodarone. Initial doses were 600-2000 mg/day and maintenance doses …

Effect of amiodarone on mortality after myocardial infarction: a double-blind, placebo-controlled, pilot study

L Ceremuzynski, E Kleczar… - Journal of the American …, 1992 - Elsevier
Objectives. The goal of this study was to evaluate the effect of amiodarone on mortality,
ventricular arrhythmias and clinical complications in high risk postinfarction patients …

Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia

H Van Herendael, P Dorian - Vascular health and risk …, 2010 - Taylor & Francis
Amiodarone has emerged as the leading antiarrhythmic therapy for termination and
prevention of ventricular arrhythmia in different clinical settings because of its proven …

Intravenous amiodarone: pharmacology, pharmacokinetics, and clinical use

MS Chow, HA Monsanto… - Annals of …, 1996 - journals.sagepub.com
Objective To review the clinical pharmacology, pharmacokinetics, and clinical efficacy and
safety of intravenous amiodarone. Data Identification Articles were identified through a …

Dose-ranging study of intravenous amiodarone in patients with life-threatening ventricular tachyarrhythmias

MM Scheinman, JH Levine, DS Cannom, T Friehling… - Circulation, 1995 - Am Heart Assoc
Background Oral amiodarone effectively suppresses ventricular arrhythmias; however, full
activity may take days or weeks. In patients with frequent, life-threatening ventricular …

Practical management guide for clinicians who treat patients with amiodarone

AE Epstein, B Olshansky, GV Naccarelli… - The American journal of …, 2016 - Elsevier
Amiodarone, an iodinated benzofuran derivative with Class I, II, III, and IV antiarrhythmic
properties, is the most commonly used antiarrhythmic drug used to treat supraventricular …

Optimal management of amiodarone therapy: efficacy and side effects

D Hilleman, MA Miller, R Parker… - … : The Journal of …, 1998 - Wiley Online Library
Objectives. To review management and dosing guidelines for amiodarone therapy, and
discuss the drug's adverse event profile. Methods. Review of relevant studies and reports …

Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects

DP Zipes, EN Prystowsky, JJ Heger - Journal of the American College of …, 1984 - Elsevier
Interest in amiodarone has increased because of its remarkable efficacy as an
antiarrhythmic agent. The purpose of this report is to review what is known about the …

Effect of prophylactic amiodarone on mortality after acute myocardial infarction and in congestive heart failure: meta-analysis of individual data from 6500 patients in …

Amiodarone Trials Meta-Analysis Investigators - The Lancet, 1997 - Elsevier
BACKGROUND: There have been 13 randomised controlled trials of prophylactic
amiodarone in patients with recent myocardial infarction (MI) or congestive heart failure …