Implicit and explicit dosimetry in photodynamic therapy: a new paradigm

BC Wilson, MS Patterson, L Lilge - Lasers in medical science, 1997 - Springer
Dosimetry for photodynamic therapy (PDT) is becoming increasingly complex as more
factors are identified which may influence the effectiveness of a given treatment. The simple …

How tissue optics affect dosimetry of photodynamic therapy

SL Jacques - Journal of biomedical optics, 2010 - spiedigitallibrary.org
We describe three lessons learned about how tissue optics affect the dosimetry of red to
near-infrared treatment light during PDT, based on working with Dr. Tayyaba Hasan. Lesson …

The role of photodynamic therapy (PDT) physics

TC Zhu, JC Finlay - Medical physics, 2008 - Wiley Online Library
Photodynamic therapy (PDT) is an emerging treatment modality that employs the
photochemical interaction of three components: light, photosensitizer, and oxygen …

Revisiting photodynamic therapy dosimetry: reductionist & surrogate approaches to facilitate clinical success

BW Pogue, JT Elliott, SC Kanick… - Physics in Medicine …, 2016 - iopscience.iop.org
Photodynamic therapy (PDT) can be a highly complex treatment, with many parameters
influencing treatment efficacy. The extent to which dosimetry is used to monitor and …

Light sources and dosimetry techniques for photodynamic therapy

MM Kim, A Darafsheh - Photochemistry and photobiology, 2020 - Wiley Online Library
Effective treatment delivery in photodynamic therapy (PDT) requires coordination of the light
source, the photosensitizer, and the delivery device appropriate to the target tissue. Lasers …

Photodynamic Therapy: Critical PDT Theory

D Kessel - Photochemistry and photobiology, 2023 - Wiley Online Library
Photodynamic therapy can be useful for the eradication of malignant cells at sites that are
accessible to light delivery. There are few adverse effects, with many clinical reports …

The theory of photodynamic therapy dosimetry: Consequences of photo‐destruction of sensitizer

WR Potter, TS Mang… - Photochemistry and …, 1987 - Wiley Online Library
Photodynamic dose is defined as the area under the curve of sensitizer level plotted as a
function of light dose. This is a photochemical definition of dose. We will show that this …

Art and science of photodynamic therapy

S Pervaiz, M Olivo - Clinical and experimental pharmacology …, 2006 - Wiley Online Library
SUMMARY 1 Photodynamic therapy is an established modality for the treatment of solid
tumours and other accessible lesions. Although the concept and practice of combining light …

Dosimetry model for photodynamic therapy with topically administered photosensitizers

LO Svaasand, P Wyss, MT Wyss, Y Tadir… - Lasers in Surgery …, 1996 - Wiley Online Library
Abstract Background and Objective Photodynamic therapy (PDT) based on topical
application of photosensitizers has been under development over the last years. Typical …

Quantitative reflectance spectrophotometry for the noninvasive measurement of photosensitizer concentration in tissue during photodynamic therapy

MS Patterson, E Schwartz… - Photodynamic Therapy …, 1989 - spiedigitallibrary.org
When light is diffusely reflected from tissue containing a dye, such as a photosensitizer, with
a known absorption spectrum, the changes in the reflectance spectrum caused by the …