Key Principles and Clinical Applications of “Next-Generation” DNA Sequencing
JM Rizzo, MJ Buck - Cancer prevention research, 2012 - AACR
Demand for fast, inexpensive, and accurate DNA sequencing data has led to the birth and
dominance of a new generation of sequencing technologies. So-called “next-generation” …
dominance of a new generation of sequencing technologies. So-called “next-generation” …
[PDF][PDF] Generations of sequencing technologies: from first to next generation
DNA sequencing process utilizes biochemical methods in order to determine the correct
order of nucleotide bases in a DNA macromolecule using sequencing machines. Ten years …
order of nucleotide bases in a DNA macromolecule using sequencing machines. Ten years …
Massively parallel sequencing techniques for forensics: A review
B Bruijns, R Tiggelaar, H Gardeniers - Electrophoresis, 2018 - Wiley Online Library
DNA sequencing, starting with Sanger's chain termination method in 1977 and evolving into
the next generation sequencing (NGS) techniques of today that employ massively parallel …
the next generation sequencing (NGS) techniques of today that employ massively parallel …
Massively parallel sequencing: the next big thing in genetic medicine
T Tucker, M Marra, JM Friedman - The American Journal of Human …, 2009 - cell.com
Massively parallel sequencing has reduced the cost and increased the throughput of
genomic sequencing by more than three orders of magnitude, and it seems likely that costs …
genomic sequencing by more than three orders of magnitude, and it seems likely that costs …
Perspectives and challenges of emerging single‐molecule DNA sequencing technologies
M Xu, D Fujita, N Hanagata - Small, 2009 - Wiley Online Library
The growing demand for analysis of the genomes of many species and cancers, for
understanding the role of genetic variation among individuals in disease, and with the …
understanding the role of genetic variation among individuals in disease, and with the …
A glimpse into past, present, and future DNA sequencing
M Morey, A Fernández-Marmiesse… - Molecular genetics and …, 2013 - Elsevier
Current advances in DNA sequencing technologies are dropping down sequencing cost
while increasing throughput at a pace never shown before. Past-decade great milestones …
while increasing throughput at a pace never shown before. Past-decade great milestones …
Massively parallel sequencing: the new frontier of hematologic genomics
JM Johnsen, DA Nickerson… - Blood, The Journal of the …, 2013 - ashpublications.org
Genomic technologies are becoming a routine part of human genetic analysis. The
exponential growth in DNA sequencing capability has brought an unprecedented …
exponential growth in DNA sequencing capability has brought an unprecedented …
The application of long-read sequencing in clinical settings
Long-read DNA sequencing technologies have been rapidly evolving in recent years, and
their ability to assess large and complex regions of the genome makes them ideal for clinical …
their ability to assess large and complex regions of the genome makes them ideal for clinical …
Human genome sequencing at the population scale: a primer on high-throughput DNA sequencing and analysis
Most human diseases have underlying genetic causes. To better understand the impact of
genes on disease and its implications for medicine and public health, researchers have …
genes on disease and its implications for medicine and public health, researchers have …
Long-read DNA sequencing: recent advances and remaining challenges
PE Warburton, RP Sebra - Annual review of genomics and …, 2023 - annualreviews.org
DNA sequencing has revolutionized medicine over recent decades. However, analysis of
large structural variation and repetitive DNA, a hallmark of human genomes, has been …
large structural variation and repetitive DNA, a hallmark of human genomes, has been …