Microfluidic technologies have been extensively investigated in recent years for developing
organ-on-a-chip-devices as robust in vitro models aiming to recapitulate organ 3D …

The human gut is important for food digestion and absorption, as well as a venue for a large
number of microorganisms that coexist with the host. Although numerous in vitro models …

The intestinal epithelium has one of the highest turnover rates in the human body, which is
supported by intestinal stem cells. Culture models of intestinal physiology have been …

The gut-on-a-chip is a microengineered in vitro model of the living human intestine that
reconstitutes the lumen-capillary tissue interface. Intestinal epithelial Caco-2 cells cultured …

The intestinal microbiome affects a number of biological functions of the organism. Although
the animal model is a powerful tool to study the relationship between the host and microbe …

The human gut extracts nutrients from the diet while forming the largest barrier against the
outer environment. In addition, the gut actively maintains homeostasis through intricate …

Over the past decade, microfluidic intestine-on-a-chip models have been emerging as a
novel platform to study intestinal function in health and disease. These microphysiological …

Overwhelming scientific evidence today confirms that the gut microbiota is a central player in
human health. Knowledge about interactions between human gut microbiota and human …

Microfluidic organ-on-a-chip models of human intestine have been developed and used to
study intestinal physiology and pathophysiology. In this article, we review this field and …

Background The interaction between diet and gut microbiota plays a critical role in human
health. While the conventional in vitro models cannot faithfully recapitulate the intestinal …