Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …

Long noncoding RNAs (lncRNAs) represent a newly discovered class of regulatory
molecules that impact a variety of biological processes in cells and organ systems. In …

The discovery of long noncoding RNAs (lncRNA) has provided a new perspective on gene
regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that …

It is increasingly clear that long non-coding RNAs (lncRNAs) regulate a variety biological
responses, and that they do so by a diverse range of mechanisms. In the field of …

Long noncoding RNAs (lncRNAs) are emerging as critical regulators of gene expression in
the immune system. Studies have shown that lncRNAs are expressed in a highly lineage …

The identification of RNAs that are not translated into proteins was an important
breakthrough, defining the diversity of molecules involved in eukaryotic regulation of gene …

The immune system is composed of diverse cell types that coordinate responses to infection
and maintain tissue homeostasis. In each of these cells, extracellular cues determine highly …

Highlights•lncRNAs are the largest class of non-coding RNA genes in mammalian
genomes.•lncRNAs are expressed in a variety of immune cells.•Recent studies demonstrate …

All cells of the immune system rely on a highly integrated and dynamic gene expression
program that is controlled by both transcriptional and post-transcriptional mechanisms …

Precise and dynamic regulation of gene expression is a key feature of immunity. In recent
years, rapid advances in transcriptome profiling analysis have led to recognize long non …