A series of experiments was performed to investigate whether, after exposure of rats to a
chemical hepatocarcinogen, feeding a choline-deficient (CD) diet would promote the …

Using the procedure of Solt and Farber for the rapid induction of foci of altered hepatocytes,
we investigated the effect of a choline-devoid (CD) diet on the emergence of such foci in the …

The effect of feeding phenobarbital (PHB) with a cholinedevoid (CD) diet on the emergence
of foci of γ-glutamyltranspeptidase (GGT)-positive hepatocytes in the liver of carcinogen …

Following previous findings that feeding a choline‐deficient (CD) diet to rats strongly
promotes the evolution of liver cells, initiated by a chemical carcinogen, to foci of y …

The ingestion of an elevated level (2%) of l-tryptophan (TRP) in a purified diet was
investigated to determine whether it would influence the induction of γ …

The promoting effects of 5 bile acids on liver carcinogenesis were investigated in male
Fischer rats initially treated with diethylnitrosamine(DEN). Two weeks after a single dose of …

To extend our ongoing characterization of modulatory influences on hepatic tumorigenesis,
we examined effects of rat strain (Sprague-Dawley versus Fischer), diet composition …

The feeding for 10 or 11 weeks of young male Fischer-344 rats, a diet devoid of choline and
low in methionine, leads to the appearance of γ-glutamyltransferase-positive foci of altered …

Experiments were designed to determine the role of cell proliferation in the initiation of liver
carcinogenesis induced by chemicals. To investigate this, two methylating carcinogens, N …

Butylated hydroxytoluene (BHT) at concentrations of 300–600 ppm in the diet caused a dose-
dependent increase in γ-glutamyl transpeptidase (GGT) activity in normal F344 male rat liver …