Development of curcumin as an epigenetic agent
S Fu, R Kurzrock - Cancer, 2010 - Wiley Online Library
The clinical benefits of curcumin as a single agent were demonstrated in patients with
advanced pancreatic cancer in a phase 2 study despite pharmacokinetic analysis showing a …
advanced pancreatic cancer in a phase 2 study despite pharmacokinetic analysis showing a …
[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer
T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …
globally and is in great need of intense study on the pathogenic mechanism and effective …
Curcumin mediates anticancer effects by modulating multiple cell signaling pathways
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …
Anticancer activity of curcumin and its analogues: preclinical and clinical studies
Curcumin has been shown to have a wide variety of therapeutic effects, ranging from anti-
inflammatory, chemopreventive, anti-proliferative, and anti-metastatic. This review provides …
inflammatory, chemopreventive, anti-proliferative, and anti-metastatic. This review provides …
Critical review on curcumin as a therapeutic agent: From traditional herbal medicine to an ideal therapeutic agent
Traditionally, many natural medicinal plants have been used to treat a variety of diseases
since ancient times and are considered a potential source of phytochemicals for the …
since ancient times and are considered a potential source of phytochemicals for the …
[HTML][HTML] Curcumin―the paradigm of a multi-target natural compound with applications in cancer prevention and treatment
As cancer is a multifactor disease, it may require treatment with compounds able to target
multiple intracellular components. We summarize here how curcumin is able to modulate …
multiple intracellular components. We summarize here how curcumin is able to modulate …
Can curcumin and its analogs be a new treatment option in cancer therapy?
H Mirzaei, MJM Khoi, M Azizi, M Goodarzi - Cancer Gene Therapy, 2016 - nature.com
Since ancient times, plants are used as therapeutic agents. With increasing knowledge in
this area, it has been shown that several synthetic and biological therapies are associated …
this area, it has been shown that several synthetic and biological therapies are associated …
New insights into therapeutic activity and anticancer properties of curcumin
Natural compounds obtained from plants are capable of garnering considerable attention
from the scientific community, primarily due to their ability to check and prevent the onset …
from the scientific community, primarily due to their ability to check and prevent the onset …
Molecular targets of curcumin for cancer therapy: an updated review
PD Kasi, R Tamilselvam, K Skalicka-Woźniak… - Tumor Biology, 2016 - Springer
In recent years, natural edible products have been found to be important therapeutic agents
for the treatment of chronic human diseases including cancer, cardiovascular disease, and …
for the treatment of chronic human diseases including cancer, cardiovascular disease, and …
[HTML][HTML] Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory,
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …