WNT signals are transduced to the canonical pathway for cell fate determination, and to the
noncanonical pathway for control of cell movement and tissue polarity. Canonical WNT …

Canonical WNT signaling through Frizzled and LRP5/6 receptors is transduced to the
WNT/β-catenin and WNT/stabilization of proteins (STOP) signaling cascades to regulate cell …

WNT family members are secreted-type glycoproteins to orchestrate embryogenesis, to
maintain homeostasis, and to induce pathological conditions. FZD1, FZD2, FZD3, FZD4 …

Wnt signaling is an evolutionary cell‐to‐cell coordination mechanism and it is highly critical
for a variety of physiological processes of an organism's body, including stem cell …

Intracellular signalling mediated by secreted Wnt proteins is essential for the establishment
of cell fates and proper tissue patterning during embryo development and for the regulation …

WNT signals are transduced through seven-transmembrane-type WNT receptors encoded
by Frizzled (FZD) genes to the β-catenin-TCF pathway, the JNK pathway or the Ca2+ …

Wnt signaling plays an essential role in the initiation and progression of various types of
cancer. Besides, the Wnt pathway components have been established as reliable …

The biological functions of some orthologs within the human genome and model-animal
genomes are evolutionarily conserved, but those of others are divergent due to protein …

Wnt signaling plays a major role in regulating cell proliferation and differentiation. The Wnt
ligands are a family of 19 secreted glycoproteins that mediate their signaling effects via …

Wnt signaling pathway is one of the most important signaling pathways. The complexity of
Wnt signals and their functional role is crucial in development and growth. It is the most …