Post hoc analysis of the glutamics–trial: intravenous glutamate infusion and use of inotropic drugs after cabg

M Vidlund, B Tajik, E Håkanson, Ö Friberg, J Holm… - BMC …, 2015 - Springer
Background Intravenous glutamate reduced the risk of developing severe circulatory failure
after isolated coronary artery bypass graft surgery (CABG) for acute coronary syndrome …

[HTML][HTML] GLUTAMICS—a randomized clinical trial on glutamate infusion in 861 patients undergoing surgery for acute coronary syndrome

M Vidlund, E Håkanson, Ö Friberg… - The Journal of thoracic …, 2012 - Elsevier
OBJECTIVE: Glutamate has been claimed to protect the heart from ischemia and to facilitate
metabolic and hemodynamic recovery after ischemia. The GLUTAmate for Metabolic …

[HTML][HTML] Glutamate Infusion Reduces Myocardial Dysfunction after Coronary Artery Bypass Grafting According to NT-proBNP: Summary of 2 Randomized Controlled …

J Holm, F Vanky, R Svedjeholm - The American Journal of Clinical Nutrition, 2023 - Elsevier
Background Glutamate is reported to enhance the recovery of oxidative metabolism and
contractile function of the heart after ischemia. The effect appears to be blunted in diabetic …

The impact of glutamate infusion on postoperative NT-proBNP in patients undergoing coronary artery bypass surgery: a randomized study

H Jiang, J Holm, M Vidlund, F Vanky, Ö Friberg… - Journal of Translational …, 2020 - Springer
Background Glutamate, a key intermediate in myocardial metabolism, may enhance
myocardial recovery after ischemia and possibly reduce the incidence and severity of …

Effect of glutamate infusion on NT-proBNP after coronary artery bypass grafting in high-risk patients (GLUTAMICS II): A randomized controlled trial

J Holm, G Ferrari, A Holmgren, F Vanky, Ö Friberg… - PLoS …, 2022 - journals.plos.org
Background Animal and human data suggest that glutamate can enhance recovery of
myocardial metabolism and function after ischemia. N-terminal pro-brain natriuretic peptide …

Glutamine is cardioprotective in patients with ischemic heart disease following cardiopulmonary bypass

VV Lomivorotov, SM Efremov, VA Shmirev… - The heart surgery …, 2011 - journal.hsforum.com
Background: The aim of the present study was to investigate the cardioprotective effects of
the perioperative use of N (2)-L-alanyl-L-glutamine (GLN) in patients with ischemic heart …

The supportive value of pre-bypass L-glutamate loading in patients undergoing coronary artery bypass grafting

G Bitzikas, C Papakonstantinou… - Journal of …, 2005 - search.proquest.com
AIM: Experimental studies have demonstrated that an exogenous supply of glutamate
improves mechanical function and recovery of ischemic myocardium. The aim of the present …

Myocardial protecting role of glutamine in patients with low ejection fraction undergoing elective on-pump coronary artery bypass graft surgery

IMA Parmana, CE Boom, L Rachmadi… - Vascular Health and …, 2022 - Taylor & Francis
Purpose Myocardial injury due to on-pump coronary artery bypass grafting (CABG) in
patients with low ejection fraction (EF) is associated with poor outcomes. This study …

Cardioprotective effects of glutamine in patients with ischemic heart disease operated under conditions of extracorporeal blood circulation

VV Lomivorotov, SM Efremov, VA Shmyrev… - Anesteziologiia i …, 2012 - europepmc.org
It was conducted a study of glutamine cardioptotective effects during perioperative use in
patients with ischemic heart disease, operated under CB. Exclusion criteria were: left …

The effect of glutamate infusion on cardiac performance is independent of changes in metabolism in patients undergoing routine coronary artery bypass surgery

CJ LANGENBERG, HG PIETERSEN… - Clinical …, 2001 - portlandpress.com
In a double-blind randomized placebo-controlled study, the effects of intravenous glutamate
infusion on myocardial haemodynamics and metabolism were studied in 22 patients …