Molecular approaches to thyroid cancer diagnosis

SJ Hsiao, YE Nikiforov - Endocrine-related cancer, 2014 - erc.bioscientifica.com
Thyroid nodules are common, and the accurate diagnosis of cancer or benign disease is
important for the effective clinical management of patients. Molecular markers are a helpful …

Diagnostic use of molecular markers in the evaluation of thyroid nodules

MI Kim, EK Alexander - Endocrine Practice, 2012 - Elsevier
Objective To describe the molecular markers thus far evaluated for use in the care of
patients with clinically relevant thyroid nodules. Methods We review the currently available …

Update on molecular diagnostics in thyroid pathology: a review

B Alzumaili, PM Sadow - Genes, 2023 - mdpi.com
Thyroid nodules are quite common, and the determination of a nodule of concern is
complex, involving serum testing, radiology and, in some cases, pathological evaluation. For …

Molecular fine-needle aspiration biopsy diagnosis of thyroid nodules by tumor specific mutations and gene expression patterns

M Eszlinger, R Paschke - Molecular and cellular endocrinology, 2010 - Elsevier
Fine-needle aspiration biopsy (FNAB) is currently the most sensitive and specific tool for the
presurgical differential diagnosis of thyroid malignancy, but has also substantial limitations …

Clinical value of molecular markers as diagnostic and prognostic tools to guide treatment of thyroid cancer

P Valderrabano, M Eszlinger… - Clinical …, 2023 - Wiley Online Library
Objective Advances in our understanding of the molecular biology of thyroid tumours is
being rapidly translated into their clinical management. This review summarizes the current …

Role of molecular markers in thyroid nodule management: then and now

YE Nikiforov - Endocrine Practice, 2017 - Elsevier
Objective: To describe the evolution and clinical utility of molecular testing for thyroid
nodules and cancer achieved over the last 2 decades. Methods: Scientific reports on thyroid …

Molecular testing for thyroid nodules: the experience at McGill University teaching hospitals in Canada

M Rajab, RJ Payne, VI Forest, M Pusztaszeri - Cancers, 2022 - mdpi.com
Simple Summary The aim of this review is to provide a general overview about the
molecular markers (mutations and alterations) of thyroid cancers, present several molecular …

[HTML][HTML] Molecular diagnostics in the evaluation of thyroid nodules: Current use and prospective opportunities

J Patel, J Klopper, EE Cottrill - Frontiers in endocrinology, 2023 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy with an estimated 43,800 new
cases to be diagnosed in 2022 and representing the 7th most common cancer in women …

Molecular-directed treatment of differentiated thyroid cancer: advances in diagnosis and treatment

L Yip, JA Sosa - JAMA surgery, 2016 - jamanetwork.com
Importance Thyroid cancer incidence is increasing, and when fine-needle aspiration biopsy
results are cytologically indeterminate, the diagnosis is often still established only after …

Molecular genetics and diagnosis of thyroid cancer

YE Nikiforov, MN Nikiforova - Nature Reviews Endocrinology, 2011 - nature.com
Thyroid cancer is a common type of endocrine malignancy, and its incidence has been
steadily increasing in many regions of the world. Initiation and progression of thyroid cancer …