[HTML][HTML] In vitro anticancer assessments of Annona muricata fractions and in vitro antioxidant profile of fractions and isolated acetogenin (15-acetyl guanacone)

KC Agu, NP Okolie, A Falodun, N Engel-Lutz - Journal of Cancer Research …, 2018 - Elsevier
Annona muricata has been attributed with numerous health benefits–including anticancer
properties. The aim of this study was to carry out anticancer investigations of fractions of …

Molecular Docking and Dynamics Study of Acetogenins Targeting Cyclin-dependent Kinase and In vitro Evaluation of Annona Muricata Fruit Extracts using MDA-MB …

S Birendra, S Kotha, H Ramappa… - Letters in Drug …, 2024 - ingentaconnect.com
Background: Overexpressed CDK1 and CDK2 are targeted as potential sites for cancer
treatment. Annona muricata fruit has been reported to have more than 100 acetogenins …

Differential cytotoxic effects ofAnnona squamosa seed extracts on human tumour cell lines: Role of reactive oxygen species and glutathione

BVV Pardhasaradhi, M Reddy, AM Ali, AL Kumari… - Journal of …, 2005 - Springer
Annonaceous acetogenins are a new class of compounds that have been reported to have
potent pesticidal, parasiticidal, anti-microbial, cell growth inhibitory activities. In this study …

Ganoderic acid A holds promising cytotoxicity on human glioblastoma mediated by incurring apoptosis and autophagy and inactivating PI3K/AKT signaling pathway

Y Cheng, P Xie - Journal of Biochemical and Molecular …, 2019 - Wiley Online Library
Abstract Ganoderic acid A (GA‐A), recognized as a lanostanetriterpene isolated from
Ganoderma lucidum, demonstrates an efficient antitumor activity in multiple cancers. To …

[引用][C] Possible cytotoxic activity of Annona muricata leaves in Huh-7 human liver cancer cells

A Banerjee, A Sengupta, B Maji, A Nandi, S Pal… - Hepatol Pancreat Sci, 2017

Acetogenin extracted from annona muricata prevented the actions of EGF in PA-1 ovarian cancer cells

L Periyasamy, B Muruganantham… - Protein and Peptide …, 2021 - ingentaconnect.com
Background: In individuals with ovarian cancer, an increase in the circulating level of the
epidermal growth factor (EGF) is readily apparent. Ovarian cancer cells exhibit signaling …

[HTML][HTML] Anti-tumor effects of jaceosidin on apoptosis, autophagy, and necroptosis in human glioblastoma multiforme

KR Park, YH Jeong, JY Lee, IK Kwon… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is the most aggressive and common malignant neoplasm.
Nevertheless, a 5-year survival rate of patients with GBM has remained below 5%. Artemisia …

4-Acetylantrocamol LT3 Inhibits Glioblastoma Cell Growth and Downregulates DNA Repair Enzyme O6-Methylguanine-DNA Methyltransferase

SY Lee, IC Yen, JC Lin, MC Chung… - The American Journal of …, 2021 - World Scientific
Glioblastoma multiforme (GBM) is a deadly malignant brain tumor that is resistant to most
clinical treatments. Novel therapeutic agents that are effective against GBM are required …

[HTML][HTML] A Review on Annona muricata and Its Anticancer Activity

S Ilango, DK Sahoo, B Paital, K Kathirvel, JI Gabriel… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is becoming more prevalent, raising concerns regarding how well
current treatments work. Cancer patients frequently seek alternative treatments to surgery …

Deciphering Annona's Anticancer Potential: Comparative Analysis of Crude Extract Versus Nanoformulation on SCC-25 Oral Cancer Cells Through cell Viability …

M Rekha, S Bhuminathan, T Dineshkumar… - Journal of Maxillofacial …, 2024 - Springer
Introduction Annona muricata contains acetogenins, which have shown promising
anticancer activity against various cell lines. This study aims to evaluate and compare the …