[HTML][HTML] Induction and recovery of CpG site specific methylation changes in human bronchial cells after long-term exposure to carbon nanotubes and asbestos

D Öner, M Ghosh, R Coorens, H Bové, M Moisse… - Environment …, 2020 - Elsevier
Introduction Inhalation of asbestos induces lung cancer via different cellular mechanisms.
Together with the increased production of carbon nanotubes (CNTs) grows the concern …

Carbon nanotube-and asbestos-induced DNA and RNA methylation changes in bronchial epithelial cells

E Emerce, M Ghosh, D Öner, RC Duca… - Chemical Research …, 2019 - ACS Publications
Carbon nanotubes (CNTs) are nanoscale tube-shaped carbon materials used in many
industrial areas. Their fiber shape has caused concerns about their toxicity given their …

[HTML][HTML] Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice

G Scala, MN Delaval, SP Mukherjee, A Federico… - Carbon, 2021 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) causes inflammation and
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …

Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure

TA Brown, JW Lee, A Holian, V Porter… - …, 2016 - Taylor & Francis
Use of multi-walled carbon nanotubes (MWCNT) is growing which increases occupational
exposures to these materials. Their toxic potential makes it important to have an in-depth …

Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model

E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …

Global and gene-specific DNA methylation effects of different asbestos fibres on human bronchial epithelial cells

D Öner, M Ghosh, M Moisse, RC Duca… - Environment …, 2018 - Elsevier
Inhalation exposure to asbestos is associated with lung and pleural diseases in humans and
remains a major public health issue worldwide. Human bronchial epithelial cells (16HBE) …

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

MI Sierra, L Rubio, GF Bayón, I Cobo… - …, 2017 - Taylor & Francis
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …

Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

D Öner, M Ghosh, H Bové, M Moisse, B Boeckx… - Particle and fibre …, 2018 - Springer
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …

Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells

L Wang, TA Stueckle, A Mishra, R Derk… - …, 2014 - Taylor & Francis
Accumulating evidence indicates that carbon nanotubes (CNTs) are biopersistent and can
cause lung damage. With similar fibrous morphology and mode of exposure to asbestos, a …

Postchronic single-walled carbon nanotube exposure causes irreversible malignant transformation of human bronchial epithelial cells through DNA methylation …

J Wang, X Tian, J Zhang, L Tan, N Ouyang, B Jia… - ACS …, 2021 - ACS Publications
As environmental pollutants and possible carcinogens, carbon nanotubes (CNTs) have
recently been found to induce carcinogenesis and tumor metastasis after long-term …