Tetraploid complementation is often used to produce mice from embryonic stem cells (ESCs)
by injection of diploid (2n) ESCs into tetraploid (4n) blastocysts (ESC-derived mice). This …

The derivation of induced pluripotent stem cells (iPSCs) requires not only efficient
reprogramming methods, but also reliable markers for identification and purification of …

Porcine induced pluripotency stem cells (piPSCs) are promised in basic research, animal
husbandry and regenerative medicine. However, the efficiency of the piPSCs induction has …

Somatic cells are reprogrammed to induced pluripotent stem cells (iPSCs) by
overexpression of a combination of defined transcription factors. We generated iPSCs from …

Cellular reprogramming consists of the conversion of differentiated cells into pluripotent
cells; the so-called induced Pluripotent Stem Cells. iPSC are amenable to in vitro …

The generation of induced pluripotent stem (iPS) cells from mouse and human somatic cells
by expression of defined transcription factors (Oct4, Sox2, c-Myc, Klf4, Nanog and Lin28) is a …

The induction of pluripotency in somatic cells by transcription‐factor overexpression has
been widely regarded as one of the major breakthroughs in stem cell biology within this …

The production of induced pluripotent stem cells (iPSCs) from somatic cells provides a
means to create valuable tools for basic research and may also produce a source of patient …

Induced pluripotent stem (iPS) cells can be generated from somatic cells by transduction
with several transcription factors in mouse and human. However, direct reprogramming in …

Induced pluripotent stem cells (iPSCs) hold tremendous potential for the development of
new regenerative medicine therapies and the study of molecular mechanisms of …