Induced pluripotent stem cells (iPSCs) hold tremendous potential for the development of
new regenerative medicine therapies and the study of molecular mechanisms of …

Reprogramming of mouse and human somatic cells into induced pluripotent stem (iPS) cells
has been made possible with the expression of the transcription factor quartet Oct4, Sox2, c …

Induced pluripotent stem cells (iPSCs) have been derived from various somatic cell
populations through ectopic expression of defined factors. It remains unclear whether iPSCs …

Lineage-restricted cells can be reprogrammed to a pluripotent state through overexpression
of defined transcription factors. Here, we summarize recent progress in the direct …

Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear
contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about …

To date different cell types of various mammalian species have been reprogrammed to
induced pluripotent stem cells (iPSCs) using Yamanaka's cocktail of transcription factors …

Induced pluripotent stem (iPS) cells are human somatic cells that have been reprogrammed
to a pluripotent state. There are several hurdles to be overcome before iPS cells can be …

Induced pluripotent stem cells (iPSCs) can be derived from many mouse and human
somatic cell types by forced expression of a small number of defined reprogramming factors …

For future application of induced pluripotent stem cell (iPSC) technology, the ability to
assess the overall quality of iPSC clones will be an important issue. Here we show that the …

Human and mouse embryonic stem cells (ESCs) are derived from blastocyst-stage embryos
but have very different biological properties, and molecular analyses suggest that the …