Objective: To review the available information regarding the roles of insulin‐like growth
factor (IGF)‐IGF binding protein (IGFBP) system in ovarian physiology. Design: Studies that …

EXPERIMENTAL evidence has shown that insulinlike growth factors (IGFs) exert a variety of
effects at the level of murine, rabbit, porcine, and human ovarian cells, thereby raising the …

The role of the insulin-like growth factor (IGF) system has attracted close attention. The
activity of IGF binding proteins (IGFBPs) within the ovary has not been fully elucidated to …

Ovarian follicular development is under the influence of gonadotrophins. The manner by
which gonadotrophins achieve their role in cell replication and hormone production is …

In the ovary, insulin-like growth factors (IGFs) enhance both proliferation and differentiation
of follicular cells by potentiating gonadotropin's actions. The biological effects of IGFs are …

The insulin-like growth factor (IGF) family plays an important role in follicle development,
dominant follicle growth and steroidogenesis, and follicular atresia. Insulin-like growth factor …

Insulin-like growth factors (IGFs) I and II are two single-chain polypeptide hormones that are
structurally related to each other and to proinsulin. Among the large number of growth …

Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) have important
regulatory functions in ovarian follicular development. Although most studies have …

There is increasing evidence that growth factors modulate folliculogenesis. However their
precise role in the processes of follicular growth, differentiation and atresia is still unknown …

The insulin-like growth factors (IGF), IGF-I and IGF-II, influence ovarian follicular
development. The IGF binding proteins (IGFBPs) comprise at least six distinct species which …