BACKGROUND: The complement system is an important mediator of inflammation, which
plays a pivotal role in atherosclerosis and acute myocardial infarction (AMI). Animal studies …

Background The positive effect of reperfusion after ST-elevation myocardial infarction
(STEMI) can be reduced by ischemic/reperfusion (I/R) injury. Mannose-binding-lectin (MBL) …

The complement system has a significant role in myocardial ischemia/reperfusion injury,
being responsible for cell lysis and amplification of inflammatory response. In this context …

Background Cell adhesion molecules (CAMs) play a pivotal role in the interactions between
leukocytes, platelets, and vascular endothelium. Soluble CAMs (sCAMs) are shed from cell …

Background Acute myocardial infarction (AMI) is a potentially fatal condition, being a major
cause of death worldwide. Ischemia suffered during AMI causes tissue damage, leading to …

Objectives. Patients with chronic heart failure (CHF) have an exaggerated immune
response, endothelial damage/dysfunction, and increased risk of diabetes mellitus (DM) …

The complement system is part of the host defence response. However, considerable
evidence suggests that complement plays an important role in the pathophysiology of …

Aims Heart failure (HF) is an impending complication to myocardial infarction. We
hypothesized that the degree of complement activation reflects severity of HF following acute …

Despite improvements in treatment, coronary artery disease is still responsible for one-third
of all deaths globally, due predominantly to myocardial infarction (MI) and stroke. There is an …

Background and objectives The complement system plays an important role in the
development of acute coronary syndrome (ACS). Complement C1q is an important initial …