Quantitative phase imaging of nanoscale cell structure and dynamics

G Popescu - Methods in cell biology, 2008 - Elsevier
Quantitative phase imaging (QPI) of live cells has received significant scientific interest over
the past decade or so, mainly because it offers structure and dynamics information at the …

Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Quantitative phase imaging trends in biomedical applications

T Cacace, V Bianco, P Ferraro - Optics and Lasers in Engineering, 2020 - Elsevier
In the last decades, the understanding of the complex biological mechanisms that regulate
the life and growth of single cells and their reciprocal interaction has steadily increased. In …

[HTML][HTML] Focus: medical technology: combining three-dimensional quantitative phase imaging and fluorescence microscopy for the study of cell pathophysiology

YS Kim, SY Lee, JH Jung, S Shin, HG Choi… - The Yale Journal of …, 2018 - ncbi.nlm.nih.gov
Quantitative phase imaging (QPI) has emerged as one of the powerful imaging tools for the
study of live cells in a non-invasive manner. In particular, multimodal approaches combining …

Quantitative phase imaging in biomedicine

YK Park, C Depeursinge, G Popescu - Nature photonics, 2018 - nature.com
Quantitative phase imaging (QPI) has emerged as a valuable method for investigating cells
and tissues. QPI operates on unlabelled specimens and, as such, is complementary to …

Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications

KR Lee, K Kim, J Jung, JH Heo, S Cho, S Lee… - Sensors, 2013 - mdpi.com
A cellular-level study of the pathophysiology is crucial for understanding the mechanisms
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …

Quantitative phase imaging of live cells using fast Fourier phase microscopy

N Lue, W Choi, G Popescu, T Ikeda, RR Dasari… - Applied Optics, 2007 - opg.optica.org
Using the decomposition of an image field in two spatial components that can be
controllably shifted in phase with respect to each other, a new quantitative-phase …

Quantitative phase microscopy via optimized inversion of the phase optical transfer function

MH Jenkins, TK Gaylord - Applied optics, 2015 - opg.optica.org
Although the field of quantitative phase imaging (QPI) has wide-ranging biomedical
applicability, many QPI methods are not well-suited for such applications due to their …

Phase imaging with computational specificity (PICS) for measuring dry mass changes in sub-cellular compartments

ME Kandel, YR He, YJ Lee, THY Chen… - Nature …, 2020 - nature.com
Due to its specificity, fluorescence microscopy has become a quintessential imaging tool in
cell biology. However, photobleaching, phototoxicity, and related artifacts continue to limit …

Quantitative phase imaging for medical diagnosis

H Majeed, S Sridharan, M Mir, L Ma, E Min… - Journal of …, 2017 - Wiley Online Library
Optical microscopy is an indispensable diagnostic tool in modern healthcare. As a prime
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …