Postmortem studies have shown that airway wall thickening is present in asthmatic patients
and may play a pathophysiologic role. We investigated the presence and characteristics of …

BACKGROUND Airway wall thickening has been observed in post mortem studies of
patients with asthma. Assessment of airway wall thickening by high resolution computed …

Background: In some patients chronic asthma results in irreversible airflow obstruction. High
resolution computed tomography (HRCT) has been advocated for assessing the structural …

Airway wall thickening has been assumed to cause airway hyperresponsiveness, but a
protective effect against airway narrowing has also been suggested. We investigated the …

PURPOSE: Computed tomography studies demonstrate thickening of the asthmatic airway
wall and its relation to disease severity. We evaluated the effect of inhaled corticosteroid on …

Background To prospectively apply an automated, quantitative three-dimensional approach
to imaging and airway analysis to assess airway remodeling in asthma patients. Methods …

Background: The epithelial reticular basement membrane (Rbm) of the airway wall thickens
in patients with asthma. However, whether the thickening parallels whole airway wall …

Exaggerated airway narrowing in response to bronchoconstricting stimuli is a characteristic
feature of asthmatic subjects. It is unknown whether the site of airway narrowing differs in …

Rationale: There is limited knowledge about the relationship between respiratory symptoms
and quantitative high-resolution computed tomography measures of emphysema and airway …

Purpose To analyze and compare computed tomographic (CT) bronchial measurements in
patients with asthma and healthy subjects and to correlate bronchial morphometric …