The morbid anatomy of dementia in Parkinson's disease

ME Kalaitzakis, RKB Pearce - Acta neuropathologica, 2009 - Springer
Dementia in Parkinson's disease (PD/PDD) is a common complication with a prevalence of
up to 50%, but the specific changes underlying the cognitive decline remain undefined …

The neuropathologic substrate of Parkinson disease dementia

KA Jellinger - Acta neuropathologica, 2010 - Springer
In their recent review about the morbid anatomy of dementia, Kalaitzakis and Pearce [24]
critically discussed the impact of both cortical a-synuclein (aSyn) and Alzheimer disease …

Morphological basis of Parkinson disease-associated cognitive impairment: an update

KA Jellinger - Journal of Neural Transmission, 2022 - Springer
Cognitive impairment is one of the most salient non-motor symptoms of Parkinson disease
(PD) that poses a significant burden on the patients and carers as well as being a risk factor …

Significance of brain lesions in Parkinson disease dementia and Lewy body dementia

KA Jellinger - Dementia in Clinical Practice, 2009 - karger.com
Dementia is increasingly recognized as a common feature in patients with Parkinson
disease (PD) and dementia with Lewy bodies (DLB), both sharing many clinical and …

Morphological substrates of dementia in parkinsonism A critical update

KA Jellinger - Dementia in Parkinsonism, 1997 - Springer
Dementia in parkinsonism is caused by a variety of central nervous system (CNS) lesions, of
which the molecular and pathogenic causes are poorly understood but probably include: 1 …

The morphological basis of mental dysfunction in Parkinson's disease

KA Jellinger - Journal of the neurological sciences, 2006 - Elsevier
Mental dysfunction including dementia in Parkinson's disease (PD), the incidence of which
averages 20–40%, is suggested to have six-fold lifetime risk compared to age-matched …

Parkinson's disease dementia and potential therapeutic strategies

JN Caviness, LF Lue, CH Adler… - CNS neuroscience & …, 2011 - Wiley Online Library
Dementia in Parkinson's disease (PD‐D) has only been acknowledged in the recent three
decades, but research in this field has accelerated. The purpose of this review was to …

Neuropathologic substrates of Parkinson disease dementia

DJ Irwin, MT White, JB Toledo, SX Xie… - Annals of …, 2012 - Wiley Online Library
Objective: A study was undertaken to examine the neuropathological substrates of cognitive
dysfunction and dementia in Parkinson disease (PD). Methods: One hundred forty patients …

Pathobiology of cognitive impairment in Parkinson disease: challenges and outlooks

KA Jellinger - International Journal of Molecular Sciences, 2023 - mdpi.com
Cognitive impairment (CI) is a characteristic non-motor feature of Parkinson disease (PD)
that poses a severe burden on the patients and caregivers, yet relatively little is known about …

Dementia and visual hallucinations associated with limbic pathology in Parkinson's disease

ME Kalaitzakis, LM Christian, LB Moran… - Parkinsonism & related …, 2009 - Elsevier
The pathological basis of dementia and visual hallucinations in Parkinson's disease (PD) is
not yet fully understood. To investigate this further we have conducted a clinico-pathological …