Background Obesity promotes inflammation in adipose tissue (AT) and this is implicated in
pathophysiological complications such as insulin resistance, type 2 diabetes and …

Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

Recent findings, notably on adipokines and adipose tissue inflammation, have revised the
concept of adipose tissues being a mere storage depot for body energy. Instead, adipose …

Metabolic syndrome is a major risk factor for cardiovascular and metabolic diseases. Playing
a central role in the development of metabolic syndrome and in its clinical consequences is …

Adipose tissue (AT) lies at the crossroad of nutrition, metabolism, and immunity; AT
inflammation was proposed as a central mechanism connecting obesity with its metabolic …

Adipose tissue is a special tissue environment due to its high lipid content. Adipose tissue
macrophages (ATMs) help maintain adipose tissue homeostasis in steady state by clearing …

It is now broadly accepted that low-grade chronic inflammation associated with obesity leads
to the onset of insulin resistance and type 2 diabetes mellitus. Obesity-associated …

At least 2.8 million people die each year as a result of being overweight or obese, and the
biggest burden being obesity-related diseases. Overweight and obesity account for a major …

Obesity is associated with the accumulation of pro‐inflammatory cells in visceral adipose
tissue (VAT), which is an important underlying cause of insulin resistance and progression to …