Vitamin D, best known for its role in skeletal health, has emerged as a key regulator of innate
immune responses to microbial threat. In immune cells such as macrophages, expression of …

Atopic diseases such as atopic dermatitis (AD) are very common in industrialized countries.
Up to 15%-30% of all children and 2%-10% of all adults suffer from AD. Already in early …

Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

Immunomodulatory actions of vitamin D have been recognised for over a quarter of a
century, but it is only in the last few years that the significance of this to normal human …

Vitamin D induces a diverse range of biological effects, including important functions in bone
health, calcium homeostasis and, more recently, on immune function. The role of vitamin D …

The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …

Vitamin D is a fat-soluble nutrient that humans obtain through the diet and by synthesis in
the skin upon exposure to ultraviolet B. Vitamin D is then converted by the liver to 25 …

Vitamin D is known as a key player in calcium homeostasis and electrolyte and blood
pressure regulation. Recently, important progress has been made in understanding how the …

Normal humans of all ages have the innate ability to produce vitamin D following sunlight
exposure. Inadequate vitamin D status has shown to be associated with a wide variety of …

Background Observational studies have linked vitamin D status and infectious disease. This
association is supported by the presence of the vitamin D receptor and CYP27B1 in immune …