In vivo activation of peroxisome proliferator-activated receptor-δ protects the heart from ischemia/reperfusion injury in Zucker fatty rats
TL Yue, SS Nerurkar, W Bao, BM Jucker… - … of Pharmacology and …, 2008 - ASPET
Peroxisome proliferator-activated receptor (PPAR)-δ is a transcription factor that belongs to
the PPAR family. PPAR-δ is abundantly expressed in the heart, and its role in the heart is …
the PPAR family. PPAR-δ is abundantly expressed in the heart, and its role in the heart is …
Activation of peroxisome proliferator–activated receptor-α protects the heart from ischemia/reperfusion injury
T Yue, W Bao, BM Jucker, J Gu, AM Romanic… - Circulation, 2003 - Am Heart Assoc
Background—Peroxisome proliferator–activated receptor-α (PPAR-α) is expressed in the
heart and regulates genes involved in myocardial fatty acid oxidation (FAO). The role of …
heart and regulates genes involved in myocardial fatty acid oxidation (FAO). The role of …
The role of peroxisome proliferator-activated receptor γ in mediating cardioprotection against ischemia/reperfusion injury
CB Zhong, X Chen, XY Zhou… - Journal of …, 2018 - journals.sagepub.com
Myocardial infarction (MI) is a serious cardiovascular disease resulting in high rates of
morbidity and mortality. Although advances have been made in restoring myocardial …
morbidity and mortality. Although advances have been made in restoring myocardial …
Peroxisome proliferator‐activated receptors and inflammation: take it to heart
PJH Smeets, A Planavila, GJ Van Der Vusse… - Acta …, 2007 - Wiley Online Library
Peroxisome proliferator‐activated receptors (PPARs) are ligand‐activated transcription
factors acting as key regulators of lipid metabolism as well as modulators of inflammation …
factors acting as key regulators of lipid metabolism as well as modulators of inflammation …
Activation of peroxisome proliferator-activated receptor-β/δ attenuates myocardial ischemia/reperfusion injury in the rat
A Kapoor, M Collino, S Castiglia, R Fantozzi… - Shock, 2010 - journals.lww.com
Peroxisome proliferator-activated receptor-β/δ (PPAR-β/δ) is a transcription factor that
belongs to the PPAR nuclear hormone receptor family. There is little information about the …
belongs to the PPAR nuclear hormone receptor family. There is little information about the …
PPAR-α effects on the heart and other vascular tissues
GA Francis, JS Annicotte… - American Journal of …, 2003 - journals.physiology.org
Peroxisome proliferator-activated receptor (PPAR)-α is a member of a large nuclear receptor
superfamily whose main role is to activate genes involved in fatty acid oxidation in the liver …
superfamily whose main role is to activate genes involved in fatty acid oxidation in the liver …
Inducible Conditional Vascular‐Specific Overexpression of Peroxisome Proliferator‐Activated Receptor Beta/Delta Leads to Rapid Cardiac Hypertrophy
KD Wagner, A Vukolic, D Baudouy, JF Michiels… - PPAR …, 2016 - Wiley Online Library
Peroxisome proliferator‐activated receptors are nuclear receptors which function as ligand‐
activated transcription factors. Among them, peroxisome proliferator‐activated receptor …
activated transcription factors. Among them, peroxisome proliferator‐activated receptor …
Activation of the peroxisome proliferator-activated receptor α protects against myocardial ischaemic injury and improves endothelial vasodilatation
A Tabernero, K Schoonjans, L Jesel, I Carpusca… - BMC …, 2002 - Springer
Background The peroxisome proliferator-activated receptor α (PPARα) plays an important
role in the metabolism of lipoproteins and fatty acids, and seems to protect against the …
role in the metabolism of lipoproteins and fatty acids, and seems to protect against the …
PPARδ activation normalizes cardiac substrate metabolism and reduces right ventricular hypertrophy in congestive heart failure
BM Jucker, CP Doe, CG Schnackenberg… - Journal of …, 2007 - journals.lww.com
Previously, it was shown that selective deletion of peroxisome proliferator activated receptor
δ (PPARδ) in the heart resulted in a cardiac lipotoxicity, hypertrophy, and heart failure. The …
δ (PPARδ) in the heart resulted in a cardiac lipotoxicity, hypertrophy, and heart failure. The …
The peroxisome proliferator-activated receptor gamma (PPARγ) is highly expressed in human heart ventricles
MR Mehrabi, T Thalhammer, P Haslmayer… - Biomedicine & …, 2002 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand activated transcription
factor which regulates gene expression in various tissues. PPARγ was primarily found to be …
factor which regulates gene expression in various tissues. PPARγ was primarily found to be …