Traffic-Related Air Pollution, APOE Status, and Neurodevelopmental Outcomes among School Children Enrolled in the BREATHE Project (Catalonia, Spain)

S Alemany, N Vilor-Tejedor… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Traffic-related air pollution is emerging as a risk factor for Alzheimer's disease
(AD) and impaired brain development. Individual differences in vulnerability to air pollution …

[HTML][HTML] Air pollution exposure during pregnancy and childhood, APOE ε4 status and Alzheimer polygenic risk score, and brain structural morphology in …

E Essers, AC Binter, A Neumann, T White… - Environmental …, 2023 - Elsevier
Background Air pollution exposure is associated with impaired neurodevelopment, altered
structural brain morphology in children, and neurodegenerative disorders. Differential …

Decreases in short term memory, IQ, and altered brain metabolic ratios in urban apolipoprotein ε4 children exposed to air pollution

L Calderón-Garcidueñas… - Journal of …, 2015 - content.iospress.com
Children's urban air pollution exposures result in systemic and brain inflammation and the
early hallmarks of Alzheimer's disease (AD). The apolipoprotein E (APOE) 4 allele is the …

The relationship between air pollution and cognitive functions in children and adolescents: a systematic review

U Lopuszanska, M Samardakiewicz - Cognitive and Behavioral …, 2020 - journals.lww.com
Air pollution has a negative impact on one's health and on the central nervous system. We
decided to assess studies that evaluated the relationship between air pollution and cognitive …

Interactive and additive influences of Gender, BMI and Apolipoprotein 4 on cognition in children chronically exposed to high concentrations of PM2. 5 and ozone …

L Calderón-Garcidueñas, V Jewells… - Environmental …, 2016 - Elsevier
Children's air pollution exposures are associated with systemic and brain inflammation and
the early hallmarks of Alzheimer's disease (AD). The Apolipoprotein E (APOE) 4 allele is the …

Association of air pollution with cognitive functions and its modification by APOE gene variants in elderly women

T Schikowski, M Vossoughi, A Vierkötter, T Schulte… - Environmental …, 2015 - Elsevier
Background Epidemiological studies have shown effects of long-term exposure to air
pollution on cardiovascular and respiratory health. However, studies investigating the effects …

Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate …

L Calderón-Garcidueñas, AC Solt… - Toxicologic …, 2008 - journals.sagepub.com
Air pollution is a serious environmental problem. We investigated whether residency in cities
with high air pollution is associated with neuroinflammation/neurodegeneration in healthy …

Exposure to air pollution and risk of incident dementia in the UK Biobank

KL Parra, GE Alexander, DA Raichlen… - Environmental …, 2022 - Elsevier
Background Air pollution may cause inflammatory and oxidative stress damage to the brain,
leading to neurodegenerative disease. The association between air pollution and dementia …

Association between traffic-related air pollution in schools and cognitive development in primary school children: a prospective cohort study

J Sunyer, M Esnaola, M Alvarez-Pedrerol, J Forns… - PLoS …, 2015 - journals.plos.org
Background Air pollution is a suspected developmental neurotoxicant. Many schools are
located in close proximity to busy roads, and traffic air pollution peaks when children are at …

Apolipoprotein E4, gender, body mass index, inflammation, insulin resistance, and air pollution interactions: Recipe for Alzheimer's disease development in Mexico …

L Calderón-Garcidueñas… - Journal of Alzheimer's …, 2017 - content.iospress.com
Given the epidemiological trends of increasing Alzheimer's disease (AD) and growing
evidence that exposure and lifestyle factors contribute to AD risk and pathogenesis, attention …