Differences in Lp [a] concentrations and apo [a] polymorphs between black and white Americans
SM Marcovina, JJ Albers, E Wijsman, Z Zhang… - Journal of lipid …, 1996 - Elsevier
Lp [a] concentrations in nmol/L and apo [a] size isoforms, expressed in terms of the relative
number of apo [a] kringle 4 (K4) repeats, were determined in 3959 whites and blacks from …
number of apo [a] kringle 4 (K4) repeats, were determined in 3959 whites and blacks from …
High degree of genetic polymorphism in apolipoprotein (a) associated with plasma lipoprotein (a) levels in Japanese and Chinese populations
S Kikuchi, A Nakagawa, K Kobayashi, L Li, H Yanagi… - Human genetics, 1993 - Springer
We have developed a sensitve, high-resolution method for the analysis of the apolipoprotein
(a)[apo (a)] isoforms using sodium dodecyl sulfate (SDS)-agarose/gradient polyacrylamide …
(a)[apo (a)] isoforms using sodium dodecyl sulfate (SDS)-agarose/gradient polyacrylamide …
Studies on apolipoprotein (a) phenotypes. Part 1. Phenotype frequencies in a healthy Japanese population
A Abe, A Noma - Atherosclerosis, 1992 - Elsevier
The frequency distribution for serum lipoprotein (a)(Lp (a)) concentrations in healthy
Japanese was highly skewed, with a mean±SD of 14.6±13.6 mg/dl and a median of 11.0 …
Japanese was highly skewed, with a mean±SD of 14.6±13.6 mg/dl and a median of 11.0 …
Effects of the apolipoprotein (a) size polymorphism on the lipoprotein (a) concentration in 7 ethnic groups
C Sandholzer, DM Hallman, N Saha, G Sigurdsson… - Human genetics, 1991 - Springer
Summary Apolipoprotein (a)[apo (a)] exhibits a genetic size polymorphism explaining about
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …
Apolipoprotein [a] genotype influences isoform dominance pattern differently in African Americans and Caucasians
J Rubin, F Paultre, CH Tuck, S Holleran, RG Reed… - Journal of lipid …, 2002 - ASBMB
Abstract Plasma lipoprotein [a](Lp [a]) concentrations are inversely associated with, and
largely determined by, apolipoprotein [a](apo [a]) gene size, a highly polymorphic trait. We …
largely determined by, apolipoprotein [a](apo [a]) gene size, a highly polymorphic trait. We …
Further characterization of the plasma lipoprotein (a) distribution
W Craig, S Poulin, A Bostom, C Eaton… - Journal of Clinical …, 1995 - Wiley Online Library
The plasma lipoprotein (a)[Lp (a)] distribution in caucasians is heavily skewed to the right,
with evidence of bimodality. As there is a well‐described inverse relationship between …
with evidence of bimodality. As there is a well‐described inverse relationship between …
Contribution of the apo [a] phenotype to plasma Lp [a] concentrations shows considerable ethnic variation.
Apolipoprotein [a] polymorphism has been investigated by sodium dodecyl sulfate
polyacrylamide (5.37%) gel electrophoresis and immunoblotting using a standardized …
polyacrylamide (5.37%) gel electrophoresis and immunoblotting using a standardized …
Plasma lipoprotein (a) concentration is controlled by apolipoprotein (a)(apo (a)) protein size and the abundance of hepatic apo (a) mRNA in a cynomolgus monkey …
N Azrolan, D Gavish, JL Breslow - Journal of Biological Chemistry, 1991 - ASBMB
The cynomolgus macaque was used as a model to study lipoprotein (a)(Lp (a)). Antibodies
to Lp (a) were used in Ouchterlony and Western blot analysis to show that cynomolgus …
to Lp (a) were used in Ouchterlony and Western blot analysis to show that cynomolgus …
Genetics of the quantitative Lp (a) lipoprotein trait: III. Contribution of Lp (a) glycoprotein phenotypes to normal lipid variation
E Boerwinkle, HJ Menzel, HG Kraft, G Utermann - Human genetics, 1989 - Springer
Summary Apolipoprotein (a)[apo (a)] is a large serum glycoprotein with several genetically
determined isoforms differing in their apparent molecular weight. We determined the effects …
determined isoforms differing in their apparent molecular weight. We determined the effects …
High plasma levels of apo (a) fragments in Caucasians and African‐Americans with end‐stage renal disease: implications for plasma Lp (a) assay
V Mooser, SM Marcovina, J Wang… - Clinical genetics, 1997 - Wiley Online Library
Apolipoprotein (a)[apo (a)] is a plasma glycoprotein that is highly polymorphic in size due to
differences in the number of a tandemly arrayed cysteine‐rich repeat called kringle (K) 4 at …
differences in the number of a tandemly arrayed cysteine‐rich repeat called kringle (K) 4 at …