For quantitativePET studies, there are other approaches with different advantagesand
limitationsthat one can considerfor measuringblood TACs without arterial blood sam plings …

(2). Neither of these approaches has been particularly successful because of difficulties in
positioning detectors and the failure to eliminate signal from surrounding tissues. Of course …

When clinical positron emission tomography centres were established 5 years or more ago,
the 'business plans' were largely based on the clinical cardiological applications of PET …

TO THE EDITOR: Accurate absolute quantitation of radiopharmaceutical activity in vivo is
important for numerous clinical and research PET applications. In our laboratory, we found a …

See Reference 1. ator serves traditional imaging with an Anger-type gamma camera, it is
reasonable to believe that under the right circumstances some of these generators could be …

TOTHEEDffOR.@ In a recenteditorial, Hichwaposesthe ques tion of whether animal
scanners are really necessary for PET (1). His editorial is strongly in favor of the …

Quantitative imaging biomarkers are widely used in PET for both research and clinical
applications, yet bias in the underlying image data has not been well characterized. In the …

Conclusion: The generalmethod, basedon a dual-scanap proach, can be usedto correctfor
radiolabeledmetabolitesin tissues of interest during PET scanning. The correction accounts …

1974 Objectives Full quantitative analysis of dynamic PET studies often requires a
metabolite corrected arterial plasma input function. A whole blood input function can be …

Results: Most partial-volume-corrected heart ROI TACs overesti mated the LV samples.
Blood TACs from heart images produced statistically different estimates of K than did the LV …