[HTML][HTML] Inflammatory mechanisms in atherosclerosis

GK Hansson - Journal of Thrombosis and Haemostasis, 2009 - Elsevier
Atherosclerosis, the cause of myocardial infarction, stroke and ischemic gangrene, is an
inflammatory disease. When LDL accumulates in the intima, it activates the endothelium to …

Inflammation and atherosclerosis

GK Hansson, AKL Robertson… - Annu. Rev. Pathol …, 2006 - annualreviews.org
Atherosclerosis, the cause of myocardial infarction, stroke, and ischemic gangrene, is an
inflammatory disease. The atherosclerotic process is initiated when cholesterol-containing …

Atherosclerosis—Underlying inflammatory mechanisms and clinical implications

S Patel, DS Celermajer, S Bao - The international journal of biochemistry & …, 2008 - Elsevier
Inflammation plays an important role in the initiation and progression of atherosclerosis but
many of its underlying mechanisms remain to be explored. Atherosclerotic plaques which …

Vascular biology of atherosclerosis: overview and state of the art

P Libby - The American journal of cardiology, 2003 - Elsevier
Our current understanding of the vascular biology of atherogenesis and its clinical
manifestations suggests a pathophysiology that is much more complex than mere lipid …

Inflammatory and thrombotic mechanisms in coronary atherosclerosis

D Tousoulis, G Davies, C Stefanadis, P Toutouzas… - Heart, 2003 - heart.bmj.com
Many molecular and cellular mechanisms link inflammation and haemostatic mechanisms.
Inflammation, and perhaps chronic infection, may play important roles in the initiation and …

Research progress on the relationship between atherosclerosis and inflammation

Y Zhu, X Xian, Z Wang, Y Bi, Q Chen, X Han, D Tang… - Biomolecules, 2018 - mdpi.com
Atherosclerosis is a chronic inflammatory disease; unstable atherosclerotic plaque rupture,
vascular stenosis, or occlusion caused by platelet aggregation and thrombosis lead to acute …

Inflammation and atherosclerosis: direct versus indirect mechanisms

ME Rosenfeld - Current opinion in pharmacology, 2013 - Elsevier
It is now widely accepted that the development of atherosclerotic lesions involves a chronic
inflammatory response that includes both innate and adaptive immune mechanisms …

Inflammation during the life cycle of the atherosclerotic plaque

P Libby - Cardiovascular Research, 2021 - academic.oup.com
Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed,
inflammatory mediators likely link many traditional and emerging risk factors with …

Evolving concepts in the triad of atherosclerosis, inflammation and thrombosis

R Corti, R Hutter, JJ Badimon, V Fuster - Journal of thrombosis and …, 2004 - Springer
Recent developments into antherothrombosis, the leading cause of morbidity and mortality
in Western Society, may help to change our treatment strategy to a more casual approach …

A link between inflammation and thrombosis in atherosclerotic cardiovascular diseases: Clinical and therapeutic implications

E Oikonomou, M Leopoulou, P Theofilis… - Atherosclerosis, 2020 - Elsevier
The association between thrombosis and acute coronary syndromes is well established.
Inflammation and activation of innate and adaptive immunity are another important factor …