The pathogenesis of the antiphospholipid syndrome

B Giannakopoulos, SA Krilis - New England Journal of Medicine, 2013 - Mass Medical Soc
The antiphospholipid syndrome is a prothrombotic disorder associated with autoantibodies.
It is associated with obstetrical complications (mainly spontaneous abortion) as well as …

The antiphospholipid syndrome: from pathophysiology to treatment

S Negrini, F Pappalardo, G Murdaca, F Indiveri… - Clinical and …, 2017 - Springer
Antiphospholipid antibody syndrome (APS) is an autoimmune acquired thrombophilia
characterized by recurrent thrombosis and pregnancy morbidity in the presence of …

Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Antiphospholipid syndrome

R Cervera - Thrombosis research, 2017 - Elsevier
The antiphospholipid syndrome (APS) is defined by the development of venous and/or
arterial thromboses, often multiple, and pregnancy morbidity (mainly, recurrent fetal losses) …

Antiphospholipid syndrome: from pathogenesis to novel immunomodulatory therapies

C Comarmond, P Cacoub - Autoimmunity Reviews, 2013 - Elsevier
Antiphospholipid syndrome (APS) is characterized by recurrent thrombosis and pregnancy
morbidity in association with the persistent presence of circulating antiphospholipid …

Diagnosis and management of the antiphospholipid syndrome

D Garcia, D Erkan - New England Journal of Medicine, 2018 - Mass Medical Soc
Antiphospholipid Syndrome Antiphospholipid antibodies can induce endothelial-cell,
complement, platelet, neutrophil, and monocyte activation, leading to thrombosis, renal …

Pathogenesis and management of antiphospholipid syndrome

DRJ Arachchillage, M Laffan - British journal of haematology, 2017 - Wiley Online Library
Antiphospholipid antibodies are a heterogeneous group of autoantibodies that have clear
associations with thrombosis and pregnancy morbidity, and which together constitute the …

Antiphospholipid syndrome

M Petri - Translational Research, 2020 - Elsevier
Antiphospholipid syndrome is one of the more common acquired causes of
hypercoagulability. Its major presentations are thrombotic (arterial, venous, or …

Antiphospholipid antibodies and the antiphospholipid syndrome: pathogenic mechanisms

SS Pierangeli, PP Chen, E Raschi… - … in thrombosis and …, 2008 - thieme-connect.com
Antiphospholipid antibodies (Abs) are associated with thrombosis and are a risk factor for
recurrent pregnancy loss and obstetric complications in patients with the antiphospholipid …

Antiphospholipid syndrome: an overview

JG Hanly - Cmaj, 2003 - Can Med Assoc
ANTIPHOSPHOLIPID ANTIBODIES ARE A HETEROGENEOUS GROUP of autoantibodies
that are detected by immunoassays and functional coagulation tests. The antigenic targets …