Obstructive sleep apnea (OSA) is closely associated with cancer progression and cancer-
related mortality. N6-methyladenosine (m 6 A) is involved in the process of intermittent …

Lung cancer has surpassed breast cancer as the leading cause of cancer death in females
in developed countries and the leading cause of cancer death in males. Despite extensive …

Background The importance of mRNA methylation erased by ALKBH5 in mRNA biogenesis,
decay, and translation control is an emerging research focus. Ectopically activated YAP is …

In this study, we found that ALKBH5, a key component of the N 6-methyladenosine (m 6 A)
methyltransferase complex, was significantly elevated in uveal melanoma (UM) cell lines …

Growing evidence has revealed that hypoxia is involved in multiple stages of cancer
development. However, there are limited reports on the effects of long noncoding RNAs …

Lung cancer remains the leading cause of cancer‐related death all over the world. In spite of
the great advances made in surgery and chemotherapy, the prognosis of lung cancer …

Background Recently, increased tumor incidence and cancer-related mortality have been
reported among patients with obstructive sleep apnea (OSA). Intermittent hypoxia (IH), the …

The purpose of this study was to evaluate whether obstructive sleep apnea (OSA)-related
chronic intermittent hypoxia (CIH) influences lung cancer progression and to elucidate the …

Background The modification and regulation of N6-methyladenosine (m 6 A) at mRNA level
can affect the development and progression in various tumors. ALKBH5, as an m 6 A …

Abstract Hypoxia-inducible factor 1 (HIF-1) is a master transcriptional regulator in response
to hypoxia and its transcriptional activity is crucial for cancer cell mobility. Here we present …