Objective Secondary prevention in patients with critical limb ischemia (CLI) is crucial for the
reduction of cardiovascular morbidity and mortality. Nonetheless, current recommendations …

High-intensity statins are recommended for patients with peripheral artery disease (PAD).
Critical limb ischemia (CLI) is the most advanced presentation of PAD. The benefit of statins …

Objectives: The aim of this study was to determine the associations between statin use and
major adverse cardiovascular and cerebrovascular events (MACCE) and amputation-free …

Background Statin therapy is recommended in all patients with peripheral arterial disease
(PAD). Its impact on reduction in mortality has been well-documented, yet effect on limb …

Abstract Objective Above-knee amputations (AKAs) and below-knee amputations (BKAs)
are associated with high postoperative mortality rates. In this study, we examined factors …

Objective Statins are considered standard-of-care medical therapy for patients undergoing
lower extremity bypass (LEB) procedures for chronic limb-threatening ischemia (CLTI). It is …

The aim of the study was to determine statin drug association with patency, limb salvage
rates and survival after revascularization in patients with chronic limb ischemia. We …

OBJECTIVE: Evidence suggesting a beneficial effect of cardioprotective medications in
patients with lower extremity atherosclerosis derives largely from secondary prevention …

Background—Statins stabilize atherosclerotic plaque, decrease mortality after surgical
procedures, and are linked to anti-inflammatory effects. The objective of this study was to …

Background Statin use is recommended in all patients with peripheral arterial disease (PAD)
owing to its morbidity and mortality benefits. However, the effect of statin use on limb salvage …