Despite advances in surgical care, chemotherapy, and radiotherapy, the prognosis for
primary brain tumor patients has not significantly improved over the last two decades. Gene …

Recent progress in gene therapy has increased the need for non-invasive imaging methods
that would allow early diagnosis of successful treatment. Magnetic resonance methods …

Clinical management of brain tumors and investigations into new therapies requires the
ability to assess repeatedly the response of disease to treatment. Magnetic resonance …

Non-invasive assessment of antineoplastic response and correlation of the location,
magnitude and duration of transgene expression in vivo would be particularly useful for …

Brain tumors are a heterogeneous group of neoplasm with a diverse histological, molecular,
and genetic spectrum and a widely variable clinical course and prognosis. Although most …

Brain tumours account for less than 2% of all primary tumours, but are one of the most lethal
cancers when" life lost" years are considered. Gliomas are the most prevalent type with a …

The effective management of primary brain neoplasms remains an elusive goal in clinical
oncology where there has been a drought in improving patient survival over the past two …

Tumor gene therapy is rapidly approaching the stage where it is tested in clinical settings. To
gain the full potential of therapy and minimize patient suffering, one has to be able to assess …

BACKGROUND Over the past two decades, significant advances have been made in the
fields of virology and molecular biology, and in understanding the genetic alterations …

Glioblastoma (GBM) is a type of intracranial brain tumor, for which there is no cure. In spite of
advances in surgery, chemotherapy and radiotherapy, patients die within a year of …