The Glioblastoma (GB) field has been experiencing a therapeutic standstill since 2005,
primarily due to ineffective preclinical approaches to test anti-cancer treatments. Therefore …

This issue of Topics in Magnetic Resonance Imaging focuses on neurooncology. Many
readers will know that this has been a passion of mine for the past 2 decades. I was grateful …

Glioblastoma is an aggressive brain tumor with a dismal prognosis. Gene therapy may offer
a new option for the treatment of these patients. Several gene therapy approaches have …

Brain tumors, solid neoplasms within the brain or the central spinal canal, can often be
debilitating and difficult to treat. Glioblastoma (GBM) is the most aggressive and deadliest …

Prospective clinical trials are critical to the scientific evaluation of new treatments for brain
tumors. This paper reviews basic concepts of early and late phase prospective clinical trials …

Brain tumors comprise a broad spectrum of biological and clinical entities making it unlikely
for any single therapeutic approach to be universally applicable. In particular, malignant …

Glioblastoma multiforme represents the most common primary malignant tumor of the adult
CNS. Unfortunately, the median survival after surgical intervention alone is less than 6 …

Introduction: The post-treatment monitoring of glioma patients remains an area of active
research and development. Conventional imaging with MRI is a highly sensitive modality for …

Purpose/Objective (s) Indications for postoperative radiotherapy after meningioma resection
are controversial. DNA methylation profiling identifies meningiomas at risk for recurrence …