Purpose The aim of this study was the development of poly (D, L-lactide-co-
glycolide)(PLGA) microspheres with controlled porosity, to obtain microspheres that afford …

Abstract Poly (D, L‐lactic‐co‐glycolic) acid (PLGA)‐based sub‐micron particles are uniquely
posed to overcome limitations of conventional drug delivery systems. However, tailoring …

In the last couple of decades, use of biodegradable polymer-based microspheres has been
recognized as an interesting and promising approach for parenteral controlled delivery of …

Double-walled microspheres (DWMS), with drug localized to the particle core, present a
promising route for control of drug release rates, for example, by varying the degradation …

Spray-dried microspheres based on polysaccharides were developed and the
conformational stability and controlled release of incorporated protein were evaluated using …

In this study, a modified water-in-oil-in-oil-in-water (w1/o/o/w3) method was developed to
prepare double-walled microparticles containing ovalbumin (OVA). The microparticles were …

Over the past few decades, long acting injectable (LAI) depots of polylactide-co-glycolide
(PLGA) or polylactic acid (PLA) based microspheres have been developed for controlled …

Among the different approaches to achieve protein delivery, the use of polymers, specifically
biodegraded, holds great promise. In this work, a new microsphere delivery system …

Particulate systems have tremendous potential to achieve controlled release and targeted
delivery of drugs. However, conventional single‐layered particles have several inherent …

The poly (orthoester)(POE)–poly (d, l-lactide–co-glycolide)(50: 50)(PLGA) double-walled
microspheres with 50% POE in weight were loaded with hydrophilic bovine serum albumin …