Influence of formulation methods on the in vitro controlled release of protein from poly (ester) microspheres

HT Wang, E Schmitt, DR Flanagan… - Journal of Controlled …, 1991 - Elsevier
Abstract Poly (dl-lactide/glycolide, 50: 50) microspheres containing bovine serum albumin
(BSA) were pre-pared with and without Carbopol® 951 (a potential adjuvant agent) by o/o …

Preparation, characterization and in vitro release study of BSA-loaded double-walled glucose-poly (lactide-co-glycolide) microspheres

RH Ansary, MM Rahman, MB Awang, H Katas… - Archives of pharmacal …, 2016 - Springer
The aim of this study was to prepare a model protein, bovine serum albumin (BSA) loaded
double-walled microspheres using a fast degrading glucose core, hydroxyl-terminated poly …

Microencapsulation of protein drugs for drug delivery: strategy, preparation, and applications

G Ma - Journal of Controlled Release, 2014 - Elsevier
Abstract Bio-degradable poly (lactide)(PLA)/poly (lactide–glycolide)(PLGA) and chitosan
microspheres (or microcapsules) have important applications in Drug Delivery Systems …

Preparation and characterization of a composite PLGA and poly (acryloyl hydroxyethyl starch) microsphere system for protein delivery

BH Woo, G Jiang, YW Jo, PP DeLuca - Pharmaceutical research, 2001 - Springer
Purpose. To prepare and characterize a novel composite microsphere system based on poly
(D, L-lactide-co-glycolide)(PLGA) and poly (acryloyl hydroxyethyl starch)(acHES) hydrogel …

Hydrogel‐shelled biodegradable microspheres for sustained release of encapsulants

Y Oh, SH Kim - Journal of Polymer Science, 2022 - Wiley Online Library
Biodegradable microparticles are promising for the sustained release of encapsulated
lipophilic drugs. In particular, the microparticles with uniform size show excellent linearity of …

Designing multilayered particulate systems for tunable drug release profiles

WL Lee, P Yu, M Hong, E Widjaja, SCJ Loo - Acta Biomaterialia, 2012 - Elsevier
Triple-layered microparticles comprising poly (d, l-lactide-co-glycolide, 50: 50)(PLGA), poly (l-
lactide)(PLLA) and poly (ethylene-co-vinyl acetate, 40wt.% vinyl acetate)(EVA) were …

[HTML][HTML] Preparation and sustained-release performance of PLGA microcapsule carrier system

S Ren, C Wang, L Guo, C Xu, Y Wang, C Sun, H Cui… - Nanomaterials, 2021 - mdpi.com
Microcapsules have been widely studied owing to their biocompatibility and potential for
application in various areas, particularly drug delivery. However, the size of microcapsules is …

Preparation and Characterization of Temperature-Sensitive Poly(N-isopropylacrylamide)-b-poly(d,l-lactide) Microspheres for Protein Delivery

SQ Liu, YY Yang, XM Liu, YW Tong - Biomacromolecules, 2003 - ACS Publications
Temperature-sensitive diblock copolymers, poly (N-isopropylacrylamide)-b-poly (d, l-
lactide)(PNIPAAm-b-PLA) with different PNIPAAm contents were synthesized and utilized to …

[HTML][HTML] Development and characterization of polymeric microspheres for controlled release protein loaded drug delivery system

S Ravi, KK Peh, Y Darwis, BK Murthy… - Indian journal of …, 2008 - ncbi.nlm.nih.gov
The aim of the present work was to investigate the preparation of microspheres as potential
drug carriers for proteins, intended for controlled release formulation. The hydrophilic bovine …

Microfluidic fabrication of polymeric core-shell microspheres for controlled release applications

T Kong, J Wu, KWK Yeung, MKT To, HC Shum… - …, 2013 - pubs.aip.org
We report a facile and robust microfluidic method to fabricate polymeric core-shell
microspheres as delivery vehicles for biomedical applications. The characteristics of core …