Current focus on particulate drug delivery entails the need for increased drug loading and
sustained release of water soluble drugs. Commonly studied biodegradable polyesters …

Monodisperse PLGA–alginate core–shell microspheres with controlled size and
homogeneous shells were first fabricated using capillary microfluidic devices for the purpose …

Purpose Encapsulation of liquids into biodegradable polymer microcapsules has been a
challenging task due to production limitations stemming from solution viscosity, phase …

The in vivo release characteristics of protein-loaded biodegradable microspheres were
examined in normal rats and severe combined immunodeficiency disease (SCID) mice …

Purpose Peptides are gaining significant interests as therapeutic agents due to their high
targeting specificity and potency. However, their low bioavailability and short half-lives limit …

Purpose. The acidic microclimate in poly (D, L-lactide-co-glycolide) 50/50 microspheres has
been previously demonstrated by our group as the primary instability source of …

Abstract Poly (d, l-lactide-co-glycolide)(PLGA) microspheres are attractive delivery vehicles
due to their excellent sustained release capabilities. One major problem with PLGA …

Appropriate administration of growth factors is of great importance for directing cell behavior
in regenerative medicine, which usually needs suitable carriers to protect the growth factors …

There is great interest for developing poly (lactide-co-glycolide)(PLGA) based particles for
targeted delivery and controlled release of encapsulated biological molecules. These PLGA …

Solvent extraction (or evaporation from a W1/O/W2‐dispersion), coacervation, and spray
drying methods are commonly employed to encapsulate protein drugs in polymeric …